ReviewCurrent opinion in genetics & development2015
Dynamic epithelia of the developing vertebrate face.
Review in Current opinion in genetics & development, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
13 citing papers in PubMed, 21 citations in OpenAlex.
- Nkx2.7 is a conserved regulator of craniofacial development.Nature communications · 2025Article
- Bone morphogenetic protein signaling pathway- Ethanol interactions disrupt palate formation independent of gata3.Reproductive toxicology (Elmsford, N.Y.) · 2025Article
- Gα13 controls pharyngeal endoderm convergence by regulating E-cadherin expression and RhoA activation.Development (Cambridge, England) · 2024Article
- CellRank 2: unified fate mapping in multiview single-cell data.Nature methods · 2024Article
- Pre-mandibular pharyngeal pouches in early non-teleost fish embryos.Proceedings. Biological sciences · 2023Article
- Article
- The conundrum of pharyngeal teeth origin: the role of germ layers, pouches, and gill slits.Biological reviews of the Cambridge Philosophical Society · 2022Review
- Integration of single-cell transcriptomes and chromatin landscapes reveals regulatory programs driving pharyngeal organ development.Nature communications · 2022Article
- Tbx1 and Foxi3 genetically interact in the pharyngeal pouch endoderm in a mouse model for 22q11.2 deletion syndrome.PLoS genetics · 2019Article
- Periderm invasion contributes to epithelial formation in the teleost pharynx.Scientific reports · 2019Article
- Bichir external gills arise via heterochronic shift that accelerates hyoid arch development.eLife · 2019Article
- Article
- Pharyngeal morphogenesis requires fras1-itga8-dependent epithelial-mesenchymal interaction.Developmental biology · 2016Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 1 institution in 1 country.
Funding
Abstract
A segmental series of endoderm-derived pouch and ectoderm-derived cleft epithelia act as signaling centers in the developing face. Their precise morphogenesis is therefore essential for proper patterning of the vertebrate head. Intercellular adhesion and polarity are highly dynamic within developing facial epithelial cells, with signaling from the adjacent mesenchyme controlling both epithelial character and directional migration. Endodermal and ectodermal epithelia fuse to form the primary mouth and gill slits, which involves basement membrane dissolution, cell intercalations, and apoptosis, as well as undergo further morphogenesis to generate the middle ear cavity and glands of the neck. Recent studies of facial epithelia are revealing both core programs of epithelial morphogenesis and insights into the coordinated assembly of the vertebrate head.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.