Evidence map›Paper›PMID 25747923›Full record

ReviewHarvard review of psychiatry

Treatment of co-occurring anxiety disorders and substance use disorders.

R Kathryn McHugh

Registry-linked trialAbstract readReview
In one paragraph

Review in Harvard review of psychiatry. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06676059 (SMART-r), which is not on this map. Cited by 27 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06676059 recruitingnot on this map

SMART-r: Substance Monitoring and Active Relapse Tracking Repository

TypeobservationalSponsorNational Institute on Drug Abuse (NIDA)Ran2026 to 2044Enrolled10,000ConditionsAlcoholism, Substance-Related Disorders
3 · Its place in the literature

Who cites it

27 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  13. Psychological distress in a sample of Moroccan prisoners with drug-dependence.International journal of offender therapy and comparative criminology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

R Kathryn McHughFrom Harvard Medical School and McLean Hospital, Belmont, MA.

Funding

GENDER DIFFERENCES IN MECHANISMS OF RECOVERY FROM OPIOID USE DISORDER AND ANXIETYK23DA035297 · NIDA · MCLEAN HOSPITAL · PI MCHUGH, REBECCA KATHRYN · 2014 to 2018
$959k
NIDA NIH HHS DA035297NIDA NIH HHS K23 DA035297
6 · The paper itself

Abstract

Anxiety disorders commonly co-occur with substance use disorders both in the general population and in treatment-seeking samples. This co-occurrence is associated with greater symptom severity, higher levels of disability, and poorer course of illness relative to either disorder alone. Little research has been conducted, however, on the treatment of these co-occurring disorders. This gap may not only leave anxiety untreated or undertreated but also increase the risk for relapse and poor substance use outcomes. The aim of this article is to review the current state of the literature on treating co-occurring anxiety and substance use disorders. In addition to presenting a brief overview of the epidemiology of this co-occurrence, the article discusses the challenges in assessing anxiety in the context of a substance use disorder, the evidence for various treatment approaches, and recent advances and future directions in this understudied area. Also highlighted is the need for future research to identify optimal behavioral and pharmacologic treatments for co-occurring anxiety and substance use disorders.

Indexed as

Anxiety DisordersClinical Trials as TopicCognitive Behavioral TherapyComorbidityHumansSubstance-Related Disorders

Identifiers

PMID25747923
PMCPMC4355945

What OpenQuestion holds

Textmetadata
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Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.