Evidence map›Paper›PMID 25747731›Full record

ReviewCurrent opinion in neurobiology2015

Mammalian pheromones: emerging properties and mechanisms of detection.

Lisa Stowers, Tsung-Han Kuo

Abstract readReview
In one paragraph

Review in Current opinion in neurobiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers.

0numbers the graph read from it
0cells of the map it votes in
49citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

49 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Review
  6. Article
  7. Observational
  8. Infection ofInternational journal of molecular sciences · 2023
    Article
  9. Infection withAnimals : an open access journal from MDPI · 2023
    Article
  10. Article
  11. Article
  12. How the evolution of air breathing shaped hippocampal function.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2022
    Article
  13. Review
  14. Neural circuit mechanisms that govern inter-male attack in mice.Cellular and molecular life sciences : CMLS · 2021
    Review
  15. Review
  16. Article
  17. Review
  18. Article
  19. Coding of pheromones by vomeronasal receptors.Cell and tissue research · 2021
    Review
  20. Pathogens, odors, and disgust in rodents.Neuroscience and biobehavioral reviews · 2020
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Lisa StowersDepartment of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: Stowers@scripps.edu.
Tsung-Han KuoDepartment of Molecular and Cellular Neuroscience, The Scripps Research Institute, La Jolla, CA 92037, USA. Electronic address: Kuoth@scripps.edu.

Funding

Characterization of pheromone binding proteinsR01DC006885 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI STOWERS, LISA · 2004 to 2015
$4.0M
Identification of the ligands and sensory neurons that mediate pheromone behaviorR01DC009413 · NIDCD · SCRIPPS RESEARCH INSTITUTE, THE · PI STOWERS, LISA · 2009 to 2013
$2.2M
NIDCD NIH HHS R01 DC006885NIDCD NIH HHS R01 DC009413
6 · The paper itself

Abstract

The concept of mammalian pheromones was established decades before the discovery of any bioactive ligands. Therefore, their molecular identity, native sources, and the meaning of their detection has been largely speculative. There has been recent success in identifying a variety of candidate mouse pheromones and other specialized odors. These discoveries reveal that mammalian pheromones come in a variety of ligand types and they are detected by sensory neurons that are pre-set to promote an array of social and survival behaviors. Importantly, recent findings show that they activate molecularly diverse sensory neurons that differ from canonical odorant detectors. These novel sensory neurons hold future promise to unlock the mystery of how their detection is hardwired to generate behavior.

Indexed as

AnimalsMammalsMiceOlfactory MucosaOlfactory Receptor NeuronsPheromonesSensory ThresholdsVomeronasal OrganPheromones

Identifiers

PMID25747731
PMCPMC4561034

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.