Evidence map›Paper›PMID 25747545›Full record

ArticleAmerican journal of obstetrics and gynecology2015

Morbidity and mortality associated with mode of delivery for breech periviable deliveries.

Brownsyne Tucker Edmonds, Fatima McKenzie, Michelle Macheras, Sindhu K Srinivas, Scott A Lorch

Open access · greenAbstract read
In one paragraph

Article in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 2 pooled it
3.6field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 2 syntheses or guidelines pooled it, 53 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Article
  4. Article
  5. Article
  6. Considerations for obstetric management of births 22-25 weeks' gestation.Journal of perinatology : official journal of the California Perinatal Association · 2025
    Review
  7. Observational
  8. Article
  9. Review
  10. Article
  11. Maternal morbidity by attempted route of delivery in periviable birth.The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians · 2021
    Article
  12. Medications and in-hospital outcomes in infants born at 22-24 weeks of gestation.Journal of perinatology : official journal of the California Perinatal Association · 2020
    Article
  13. Do maternal characteristics influence maternal-fetal medicine physicians' willingness to intervene when managing periviable deliveries?Journal of perinatology : official journal of the California Perinatal Association · 2016
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Brownsyne Tucker EdmondsDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN. Electronic address: btuckere@iupui.edu.
Fatima McKenzieDepartment of Obstetrics and Gynecology, Indiana University School of Medicine, Indianapolis, IN.
Michelle MacherasCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, PA.
Sindhu K SrinivasDepartment of Obstetrics and Gynecology, Perelman School of Medicine, University of Pennsylvania, Philadelphia, PA.
Scott A LorchCenter for Outcomes Research, Children's Hospital of Philadelphia, Philadelphia, PA; Division of Neonatology, Department of Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA.
Children's Hospital of Philadelphia · USIndiana University – Purdue University Indianapolis · USUniversity of Pennsylvania · US

Funding

Quality Assurance and Quality Control Project Management: Improving Submissions and Study Conduct in the Human Subjects Research Prior Approval ProcessUL1TR002529 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI MOE, SHARON M, WIEHE, SARAH ELIZABETH · 2018 to 2022
$27.2M
Indiana Clinical and Translational Sciences InstituteUL1TR001108 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI DENNE, SCOTT C., SHEKHAR, ANANTHA · 2013 to 2017
$23.3M
Indiana Clinical and Translational Science Institute-K12 ProgramKL2TR000163 · NCATS · INDIANA UNIVERSITY INDIANAPOLIS · PI SHEKHAR, ANANTHA · 2012 to 2013
$720k
NCATS NIH HHS KL2 TR000163NCATS NIH HHS UL1 TR001108
6 · The paper itself

Abstract

objectiveThe purpose of this study was to estimate the odds of morbidity and death that are associated with cesarean delivery, compared with vaginal delivery, for breech fetuses who are delivered from 23-24 6/7 weeks' gestational age. STUDY

designWe conducted a retrospective cohort study of state-level maternal and infant hospital discharge data that were linked to vital statistics for breech deliveries that occurred from 23-24 6/7 weeks' gestation in California, Missouri, and Pennsylvania from 2000-2009 (N = 1854). Analyses were stratified by gestational age (23-23 6/7 vs 24-24 6/7 weeks' gestation).

resultsCesarean delivery was performed for 46% (335 fetuses) and 77% (856 fetuses) of 23- and 24-week breech fetuses. In multivariable analyses, overall survival was greater for cesarean-born neonates (adjusted odds ratio [AOR], 3.98; 95% confidence interval [CI], 2.24-7.06; AOR, 2.91; 95% CI, 1.76-4.81, respectively). When delivered for nonemergent indications, cesarean-born survivors were more than twice as likely to experience major morbidity (intraventricular hemorrhage, bronchopulmonary dysplasia, necrotizing enterocolitis, asphyxia composite; AOR, 2.83; 95% CI, 1.37-5.84; AOR, 2.07; 95% CI, 1.11-3.86 at 23 and 24 weeks' gestation, respectively). Among intubated neonates, despite a short-term survival advantage, there was no difference in survival to >6-month corrected age (AOR, 1.77; 95% CI, 0.83-3.74; AOR, 1.50; 95% CI, 0.81-2.76, respectively). There was no difference in survival for intubated 23-week neonates who were delivered by cesarean for nonemergent indications or cesarean-born neonates who weighed <500 g.

conclusionCesarean delivery increased overall survival and major morbidity for breech periviable neonates. However, among intubated neonates, despite a short-term survival advantage, there was no difference in 6-month survival. Also, cesarean delivery did not increase survival for neonates who weighed <500 g. Patients and providers should discuss explicitly the trade-offs related to neonatal death and morbidity, maternal morbidity, and implications for future pregnancies.

Indexed as

Delivery, ObstetricAdolescentAdultAsphyxia NeonatorumBreech PresentationBronchopulmonary DysplasiaCerebral HemorrhageCesarean SectionEnterocolitis, NecrotizingFemaleFetal DeathHumansInfant, NewbornMorbidityPregnancySurvival Analysisbreechmode of deliveryoutcomeperiviable birth

Identifiers

PMID25747545
PMCPMC4533902
OpenAlexW1963924066

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.