Observational studyAmerican journal of obstetrics and gynecology2015
NuMoM2b Sleep-Disordered Breathing study: objectives and methods.
Observational study in American journal of obstetrics and gynecology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01322529 (Preterm Birth in Nulliparous Women), which is not on this map. Cited by 28 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Preterm Birth in Nulliparous Women: An Understudied Population at Great Risk
Who cites it
28 citing papers in PubMed.
- Sleep-disordered Breathing in Pregnancy and after Delivery: Associations with Cardiometabolic Health.American journal of respiratory and critical care medicine · 2022Trial
- Sleep quality measured by cardiopulmonary coupling spectrogram in pregnant women predicts neonatal outcomes.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2025Article
- Association of maternal nocturnal heart rate and adverse pregnancy outcomes.Pregnancy (Hoboken, N.J.) · 2025Article
- Sleep health in pregnancy.Sleep and biological rhythms · 2025Article
- Persistent Short Sleep Duration From Pregnancy to 2 to 7 Years After Delivery and Metabolic Health.JAMA network open · 2024Article
- Review
- Obstructive Sleep Apnea in Pregnancy: A Comprehensive Review of Maternal and Fetal Implications.Neurology international · 2024Review
- Article
- Sleep medicine clinical pearls: understanding the dynamic changes in sleep apnea during pregnancy due to hormonal shifts.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2024Article
- Multifractal analysis of heart rate variability in pregnancy during sleep.Frontiers in cardiovascular medicine · 2024Article
- Longitudinal Sleep Study in Pregnancy: Cohort Profile and Prevalence and Risk Factors for Sleep Symptoms in the First Trimester.International journal of environmental research and public health · 2023Article
- PSG-Audio, a scored polysomnography dataset with simultaneous audio recordings for sleep apnea studies.Scientific data · 2021Article
- Objectively assessed sleep-disordered breathing during pregnancy and infant birthweight.Sleep medicine · 2021Observational
- Associations Between Sleep Disorders and Hypertensive Disorders of Pregnancy and Materno-fetal Consequences.Current hypertension reports · 2020Review
- Later sleep timing is associated with an increased risk of preterm birth in nulliparous women.American journal of obstetrics & gynecology MFM · 2019Article
- Prospective Evaluation of Maternal Sleep Position Through 30 Weeks of Gestation and Adverse Pregnancy Outcomes.Obstetrics and gynecology · 2019Observational
- Article
- Association of Adverse Pregnancy Outcomes With Self-Reported Measures of Sleep Duration and Timing in Women Who Are Nulliparous.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018Article
- A review of the associations between obstructive sleep apnea and hypertensive disorders of pregnancy and possible mechanisms of disease.Sleep medicine reviews · 2018Review
- Working Together to Address Women's Health in Research and Drug Development: Summary of the 2017 Women's Health Congress Preconference Symposium.Journal of women's health (2002) · 2018Article
Corrections and comments
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Authors and funding
21 authors.
Funding
Abstract
objectiveThe objective of the Sleep Disordered Breathing substudy of the Nulliparous Pregnancy Outcomes Study Monitoring Mothers-to-be (nuMoM2b) is to determine whether sleep disordered breathing during pregnancy is a risk factor for adverse pregnancy outcomes. STUDY
designNuMoM2b is a prospective cohort study of 10,037 nulliparous women with singleton gestations that was conducted across 8 sites with a central Data Coordinating and Analysis Center. The Sleep Disordered Breathing substudy recruited 3702 women from the cohort to undergo objective, overnight in-home assessments of sleep disordered breathing. A standardized level 3 home sleep test was performed between 6(0)-15(0) weeks' gestation (visit 1) and again between 22(0)-31(0) weeks' gestation (visit 3). Scoring of tests was conducted by a central Sleep Reading Center. Participants and their health care providers were notified if test results met "urgent referral" criteria that were based on threshold levels of apnea hypopnea indices, oxygen saturation levels, or electrocardiogram abnormalities but were not notified of test results otherwise. The primary pregnancy outcomes to be analyzed in relation to maternal sleep disordered breathing are preeclampsia, gestational hypertension, gestational diabetes mellitus, fetal growth restriction, and preterm birth.
resultsObjective data were obtained at visit 1 on 3261 women, which was 88.1% of the studies that were attempted and at visit 3 on 2511 women, which was 87.6% of the studies that were attempted. Basic characteristics of the substudy cohort are reported in this methods article.
conclusionThe substudy was designed to address important questions regarding the relationship of sleep-disordered breathing on the risk of preeclampsia and other outcomes of relevance to maternal and child health.
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