Evidence map›Paper›PMID 25745498›Full record

ArticleAIDS research and therapy2014

Acute tubular nephropathy in a patient with acute HIV infection: review of the literature.

Jintanat Ananworanich, Anandita A Datta, James Lk Fletcher, Natavudh Townamchai, Nitiya Chomchey, Eugene Kroon, Irini Sereti, Victor Valcour, Jerome H Kim

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in AIDS research and therapy, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 86% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 2 countries.

Jintanat AnanworanichSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand ; Department of Medicine, Faculty of Medicine, Chulalongkorn University, 1873 Rama IV, Pathumwan, Bangkok 10330 Thailand ; US Military HIV Research Program, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 USA ; US Military HIV Research Program, Henry M. Jackson Foundation for the Advancement of Military Medicine, 6720A Rockledge Drive, Suite 400, Bethesda, MD 20817 USA.
Anandita A DattaDivision of Nephropathology, Joint Pathology Center, 606 Stephen Sitter Avenue, Silver Spring, MD 20910 USA.
James Lk FletcherSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Natavudh TownamchaiDepartment of Medicine, Faculty of Medicine, Chulalongkorn University, 1873 Rama IV, Pathumwan, Bangkok 10330 Thailand.
Nitiya ChomcheySEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Eugene KroonSEARCH, The Thai Red Cross AIDS Research Centre, Bangkok, Thailand.
Irini SeretiClinical and Molecular Retrovirology Section/ Laboratory of Immunoregulation, 10 Center Drive, building 10, room 11B-07A, Bethesda, MD 20892 USA.
Victor ValcourMemory and Aging Center, University of California at San Francisco, Suite 905, 350 Parnassus Avenue, San Francisco, CA 94143 USA.
Jerome H KimUS Military HIV Research Program, Walter Reed Army Institute of Research, 503 Robert Grant Avenue, Silver Spring, MD 20910 USA.
Thai Red Cross Society · THArkana Laboratories · USChulalongkorn University · THUniversity Memory and Aging Center · USWalter Reed Army Institute of Research · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a 57-year old man with diabetes mellitus and hypertension who presented with acute HIV infection. Routine blood tests showed an elevated blood urea nitrogen and creatinine. Renal biopsy showed acute tubular nephropathy, which has not been reported to occur during acute HIV infection, in the absence of rhabdomyolysis or multiple organ system failure. Antiretroviral therapy was initiated. His renal failure gradually resolved without further intervention. At one year of follow-up his HIV RNA was undetectable, and his renal function was normal. The case illustrates a rare manifestation of acute HIV infection - acute renal failure - in an older man with diabetes and hypertension. In this setting acute kidney injury might mistakenly have been attributed to his chronic comorbidities, and this case supports early HIV-1 testing in the setting of a high index of suspicion.

Indexed as

Acute HIV infectionAcute renal failureAcute retroviral syndromeAcute tubular nephropathyElderlyHIV

Identifiers

PMID25745498
PMCPMC4350645
OpenAlexW2100459592

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.