Evidence map›Paper›PMID 25745492›Full record

ArticleInternational journal of endocrinology and metabolism2015

A case report of thyroid carcinoma confined to ovary and concurrently occult in the thyroid: is conservative treatment always advised?

Nunzia Brusca, Susanna Carlotta Del Duca, Rita Salvatori, Antonio D'Agostini, Pina Cannas, Maria Giulia Santaguida, Camilla Virili, Loredana Bianchi, Lucilla Gargano, Marco Centanni

Open access · hybridAbstract readCase Reports
In one paragraph

Article in International journal of endocrinology and metabolism, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Nunzia BruscaDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.
Susanna Carlotta Del DucaDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.
Rita SalvatoriDepartment of Nuclear Medicine, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Antonio D'AgostiniDepartment of Nuclear Medicine, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Pina CannasDepartment of Nuclear Medicine, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Maria Giulia SantaguidaDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.
Camilla ViriliDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy.
Loredana BianchiEndocrinology Unit, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Lucilla GarganoEndocrinology Unit, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Marco CentanniDepartment of Medico-Surgical Sciences and Biotechnologies, "Sapienza" University of Rome, Latina, Italy ; Endocrinology Unit, Santa Maria Goretti Hospital, AUSL Latina, Latina, Italy.
Ospedale Santa Maria Goretti · ITSapienza University of Rome · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionStruma ovarii is an ovarian teratoma, represented in more than 50% by thyroid tissue. Five percent of struma ovarii cases have been proven to be malignant and, as in the thyroid gland, papillary thyroid carcinoma is the most common histotype arising in struma ovarii. Because of the unusual occurrence of this tumor, its management and follow-up after pelvic surgery is still controversial. Usually, total thyroidectomy followed by radioiodine treatment is the choice treatment in metastatic malignant struma ovarii, while these procedures are still controversial in non-metastatic thyroid cancer arising in struma ovarii. CASE PRESENTATION: We report a female with follicular variant of papillary thyroid carcinoma arising in struma ovarii. After pelvic surgery, thyroid morphofunctional examinations were performed and a single nodular lesion in the left lobe was discovered. The patient underwent total thyroidectomy and histological examination showed a papillary carcinoma. Radioiodine-ablation of residual thyroid tissue was performed and levothyroxine mildly-suppressive treatment was started.

conclusionsA more aggressive treatment should not be denied for malignant struma ovarii without any evidence, even when apparently confined into the ovary. However, in selected cases, aggressive treatment may be advisable to decrease the risk of recurrence and to allow an accurate follow-up.

Indexed as

Struma OvariiThyroid CarcinomaThyroidectomy

Identifiers

PMID25745492
PMCPMC4338667
OpenAlexW2137977283

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.