Evidence map›Paper›PMID 25745462›Full record

ArticleNeural regeneration research2012

Immune reactions and nerve repair in mice with sciatic nerve injury 14 days after intraperitoneal injection of Brazil.

Jian Cao, Zhongping Niu, Yongan Wang, Yiwen Jiang, Haoyu Liu, Binfeng Wang, Weitian Yin, Lisen Li

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Neural regeneration research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jian CaoSecond Department of Orthopedics, Chifeng Municipal Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China.
Zhongping NiuSecond Department of Orthopedics, Chifeng Municipal Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China.
Yongan WangSecond Department of Orthopedics, Chifeng Municipal Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China.
Yiwen JiangSecond Department of Orthopedics, Chifeng Municipal Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China.
Haoyu LiuDepartment of Hand Surgery, China-Japanese Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Binfeng WangSecond Department of Orthopedics, Chifeng Municipal Hospital, Chifeng 024000, Inner Mongolia Autonomous Region, China.
Weitian YinDepartment of Hand Surgery, China-Japanese Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.
Lisen LiDepartment of Hand Surgery, China-Japanese Union Hospital of Jilin University, Changchun 130033, Jilin Province, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

BALB/c mice were intraperitoneally injected with 10, 5 or 2.5 mg/kg Brazil for 14 days after sciatic nerve injury. Results demonstrate that the spleen T/B lymphocyte stimulation index and serum circulating immune complex concentration were significantly reduced, and the morphology of the soleus muscle was restored in mice with sciatic nerve injury. These effects of Brazil were dose-dependent. Our experimental findings indicate that Brazil can regulate immune responses after nerve injury and promote sciatic nerve repair.

Indexed as

Brazilimmuneneural regenerationperipheral nerve injuryrepair

Identifiers

PMID25745462
PMCPMC4347007

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.