Evidence map›Paper›PMID 25745448›Full record

ArticleNeural regeneration research2012

Protective effects of remote ischemic preconditioning in rat hindlimb on ischemia- reperfusion injury.

Ying Zhang, Xiangrong Liu, Feng Yan, Lianqiu Min, Xunming Ji, Yumin Luo

Abstract read
In one paragraph

Article in Neural regeneration research, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 2 pooled it
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 2 syntheses or guidelines pooled it, 20 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
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  6. Involvement of Endothelin-1, HCellular and molecular neurobiology · 2019
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 1 institution in 1 country.

Ying ZhangCerebrovascular Diseases Research Institute, Xuanwu Hospital, Capital Medical University, Ministry of Education, Beijing 100053, China ; Department of Neurology, Xuanwu Hospital of Capital Medical University, Capital Medical University, Ministry of Education, Beijing 100053, China.
Xiangrong LiuCerebrovascular Diseases Research Institute, Xuanwu Hospital, Capital Medical University, Ministry of Education, Beijing 100053, China ; Key Laboratory of Neurodegenerative Diseases, Capital Medical University, Ministry of Education, Beijing 100053, China.
Feng YanCerebrovascular Diseases Research Institute, Xuanwu Hospital, Capital Medical University, Ministry of Education, Beijing 100053, China ; Key Laboratory of Neurodegenerative Diseases, Capital Medical University, Ministry of Education, Beijing 100053, China.
Lianqiu MinDepartment of Neurology, Affiliated Hospital of Liaoning Medical University, Jinzhou 121000, Liaoning Province, China.
Xunming JiCerebrovascular Diseases Research Institute, Xuanwu Hospital, Capital Medical University, Ministry of Education, Beijing 100053, China ; Key Laboratory of Neurodegenerative Diseases, Capital Medical University, Ministry of Education, Beijing 100053, China.
Yumin LuoCerebrovascular Diseases Research Institute, Xuanwu Hospital, Capital Medical University, Ministry of Education, Beijing 100053, China ; Key Laboratory of Neurodegenerative Diseases, Capital Medical University, Ministry of Education, Beijing 100053, China.
Jinzhou Medical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Three cycles of remote ischemic pre-conditioning induced by temporarily occluding the bilateral femoral arteries (10 minutes) prior to 10 minutes of reperfusion were given once a day for 3 days before the animal received middle artery occlusion and reperfusion surgery. The results showed that brain infarct volume was significantly reduced after remote ischemic pre-conditioning. Scores in the forelimb placing test and the postural reflex test were significantly lower in rats having undergone remote ischemic pre-conditioning compared with those who did not receive remote ischemic pre-conditioning. Thus, neurological function was better in rats having undergone remote ischemic pre-conditioning compared with those who did not receive remote ischemic pre-conditioning. These results indicate that remote ischemic pre-conditioning in rat hindlimb exerts protective effects in ischemia-reperfusion injury.

Indexed as

cerebral ischemia-reperfusionneural regenerationremote ischemic preconditioningstroke

Identifiers

PMID25745448
PMCPMC4346981
OpenAlexW1521319807

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.