Evidence map›Paper›PMID 25745428›Full record

ReviewFrontiers in plant science2015

Structural basis and functions of abscisic acid receptors PYLs.

Xing L Zhang, Lun Jiang, Qi Xin, Yang Liu, Jian X Tan, Zhong Z Chen

Open access · goldAbstract readReview
In one paragraph

Review in Frontiers in plant science, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.

0numbers the graph read from it
0cells of the map it votes in
42citing papers in PubMed
13.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

42 citing papers in PubMed, 88 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Molecular profiling ofFrontiers in plant science · 2025
    Article
  8. Review
  9. Overexpression of PotatoInternational journal of molecular sciences · 2024
    Article
  10. Article
  11. Article
  12. Characterization ofPeerJ · 2024
    Article
  13. Review
  14. Article
  15. A Potential ABA Analog to Increase Drought Tolerance inInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Xing L ZhangDepartment of Pediatrics, Affiliated Hospital of Guangdong Medical College Zhanjiang, China.
Lun JiangState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University Beijing, China.
Qi XinNational Center for Nanoscience and Technology Beijing, China.
Yang LiuState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University Beijing, China.
Jian X TanDepartment of Pediatrics, Affiliated Hospital of Guangdong Medical College Zhanjiang, China.
Zhong Z ChenState Key Laboratory of Agrobiotechnology, College of Biological Sciences, China Agricultural University Beijing, China.
University of Minnesota · USNational Center for Nanoscience and Technology · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abscisic acid (ABA) plays a key role in many developmental processes and responses to adaptive stresses in plants. Recently, a new family of nucleocytoplasmic PYR/PYL/RCAR (PYLs) has been identified as bona fide ABA receptors. PYLs together with protein phosphatases type-2C (PP2Cs), Snf1 (Sucrose-non-fermentation 1)-related kinases subfamily 2 (SnRK2s) and downstream substrates constitute the core ABA signaling network. Generally, PP2Cs inactivate SnRK2s kinases by physical interaction and direct dephosphorylation. Upon ABA binding, PYLs change their conformations and then contact and inhibit PP2Cs, thus activating SnRK2s. Here, we reviewed the recent progress in research regarding the structures of the core signaling pathways of ABA, including the (+)-ABA, (-)-ABA and ABA analogs pyrabactin as well as 6AS perception by PYLs, SnRK2s mimicking PYLs in binding PP2Cs. PYLs inhibited PP2Cs in both the presence and absence of ABA and activated SnRK2s. The present review elucidates multiple ABA signal perception and transduction by PYLs, which might shed light on how to design small chemical compounds for improving plant performance in the future.

Indexed as

ABA analogsabscisic acidcrystal structuresPP2CsPYR/PYL/RCARSnRK2s

Identifiers

PMID25745428
PMCPMC4333806
OpenAlexW2104720038

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.