ReviewThe Yale journal of biology and medicine2015
Prospective MEG biomarkers in ASD: pre-clinical evidence and clinical promise of electrophysiological signatures.
Review in The Yale journal of biology and medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
31 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Coactivation of Autonomic and Central Nervous Systems During Processing of Socially Relevant Information in Autism Spectrum Disorder: A Systematic Review.Neuropsychology review · 2024Pooled it
- Autism Spectrum Disorder and auditory sensory alterations: a systematic review on the integrity of cognitive and neuronal functions related to auditory processing.Journal of neural transmission (Vienna, Austria : 1996) · 2023Pooled it
- Meta-analysis and systematic review of the literature characterizing auditory mismatch negativity in individuals with autism.Neuroscience and biobehavioral reviews · 2018Pooled it
- Auditory processing and communication in autism: exploring verbal abilities and vocal affective cues.Frontiers in psychiatry · 2026Article
- Differential alterations of thalamic subregions in children and adolescents with attention deficit hyperactivity disorder and comorbid internalizing/externalizing disorders.BMC psychiatry · 2025Article
- Lower Cortical Activation and Altered Functional Connectivity Characterize Passive Auditory Spatial Attention in ASD.Autism research : official journal of the International Society for Autism Research · 2025Article
- Lower cortical activation and altered functional connectivity characterize passive auditory spatial attention in ASD.bioRxiv : the preprint server for biology · 2025Article
- The Effect of Attention on Auditory Processing in Adults on the Autism Spectrum.Journal of autism and developmental disorders · 2024Article
- Design and methodology for a proof of mechanism study of individualized neuronavigated continuous Theta burst stimulation for auditory processing in adolescents with autism spectrum disorder.Frontiers in psychiatry · 2024Article
- The mismatch negativity as an index of cognitive abilities in adults with Down syndrome.Cerebral cortex (New York, N.Y. : 1991) · 2023Article
- Rapid auditory processing of puretones is associated with basic components of language in individuals with autism spectrum disorders.Brain and language · 2023Article
- Associations between rapid auditory processing of speech sounds and specific verbal communication skills in autism.Frontiers in psychology · 2023Article
- MEG Theta during Lexico-Semantic and Executive Processing Is Altered in High-Functioning Adolescents with Autism.Cerebral cortex (New York, N.Y. : 1991) · 2021Article
- Magnetoencephalography Research in Pediatric Autism Spectrum Disorder.Neuroimaging clinics of North America · 2020Review
- Dysregulated oscillatory connectivity in the visual system in autism spectrum disorder.Brain : a journal of neurology · 2019Article
- Revisiting the excitation/inhibition imbalance hypothesis of ASD through a clinical lens.The British journal of radiology · 2019Review
- Parvalbumin Cell Ablation of NMDA-R1 Leads to Altered Phase, But Not Amplitude, of Gamma-Band Cross-Frequency Coupling.Brain connectivity · 2019Article
- Brain Functional Connectivity Through Phase Coupling of Neuronal Oscillations: A Perspective From Magnetoencephalography.Frontiers in neuroscience · 2019Review
- Delayed M50/M100 evoked response component latency in minimally verbal/nonverbal children who have autism spectrum disorder.Molecular autism · 2019Article
- Delayed Auditory Evoked Responses in Autism Spectrum Disorder across the Life Span.Developmental neuroscience · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
Abstract
Autism spectrum disorders (ASD) are characterized by social impairments and restricted/stereotyped behaviors and currently affect an estimated 1 in 68 children aged 8 years old. While there has been substantial recent focus on ASD in research, both the biological pathology and, perhaps consequently, a fully effective treatment have yet to be realized. What has remained throughout is the hypothesis that ASD has neurobiological underpinnings and the observation that both the phenotypic expression and likely the underlying etiology is highly heterogeneous. Given the neurodevelopmental basis of ASD, a biologically based marker (biomarker) could prove useful not only for diagnostic and prognostic purposes, but also for stratification and response indices for pharmaceutical development. In this review, we examine the current state of the field for MEG-related biomarkers in ASD. We describe several potential biomarkers (middle latency delays [M50/M100], mismatch negativity latency, gamma-band oscillatory activity), and investigate their relation to symptomology, core domains of dysfunction (e.g., language impairment), and putative biological underpinnings.
Indexed as
Identifiers
25745372PMC4345535What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.