Evidence map›Paper›PMID 25745354›Full record

ArticleJournal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology2014

Modeling Population Exposures to Silver Nanoparticles Present in Consumer Products.

Steven G Royce, Dwaipayan Mukherjee, Ting Cai, Shu S Xu, Jocelyn A Alexander, Zhongyuan Mi, Leonardo Calderon, Gediminas Mainelis, KiBum Lee, Paul J Lioy and 4 more

Abstract read
In one paragraph

Article in Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology, 2014. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
  2. Article
  3. The effects of silver nanoparticles on the microbial nitrogen cycle: a review of the known risks.Environmental science and pollution research international · 2020
    Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Characterization of Airborne Particle Release from Nanotechnology-enabled Clothing Products.Journal of nanoparticle research : an interdisciplinary forum for nanoscale science and technology · 2018
    Article
  9. Article
  10. Article
  11. ModelingNanomaterials (Basel, Switzerland) · 2015
    Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Steven G RoyceEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Dwaipayan MukherjeeEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA ; Department of Chemical & Biochemical Engineering, Rutgers University, Piscataway, NJ, USA.
Ting CaiEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA ; Department of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.
Shu S XuEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Jocelyn A AlexanderEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Zhongyuan MiEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA.
Leonardo CalderonDepartment of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.
Gediminas MainelisEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.
KiBum LeeDepartment of Chemistry and Chemical Biology, Rutgers University, Piscataway, NJ, USA.
Paul J LioyEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA ; Department of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.
Teresa D TetleyNational Heart and Lung Institute, Imperial College London, London, UK.
Kian Fan ChungNational Heart and Lung Institute, Imperial College London, London, UK.
Junfeng ZhangNicholas School of the Environment and Duke Global Health Institute, Duke University, Durham, NC, USA.
Panos G GeorgopoulosEnvironmental and Occupational Health Sciences Institute (EOHSI), Rutgers University, Piscataway, NJ, USA ; Department of Environmental and Occupational Medicine, Rutgers University-Robert Wood Johnson Medical School, Piscataway, NJ, USA ; Department of Chemical & Biochemical Engineering, Rutgers University, Piscataway, NJ, USA ; Department of Environmental Sciences, Rutgers University, New Brunswick, NJ, USA.

Funding

Translational Research Support CoreP30ES005022 · NIEHS · UNIV OF MED/DENT NJ-R W JOHNSON MED SCH · PI ROBERT John LAUMBACH · 1988 to 2026
$47.4M
Scientific CoreU19ES019536 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI TETLEY, TERESA DOROTHY, ZHANG, JUNFENG · 2010 to 2014
$4.6M
NIEHS NIH HHS P30 ES005022NIEHS NIH HHS U19 ES019536
6 · The paper itself

Abstract

Exposures of the general population to manufactured nanoparticles (MNPs) are expected to keep rising due to increasing use of MNPs in common consumer products (PEN 2014). The present study focuses on characterizing ambient and indoor population exposures to silver MNPs (nAg). For situations where detailed, case-specific exposure-related data are not available, as in the present study, a novel tiered modeling system, Prioritization/Ranking of Toxic Exposures with GIS (Geographic Information System) Extension (PRoTEGE), has been developed: it employs a product Life Cycle Analysis (LCA) approach coupled with basic human Life Stage Analysis (LSA) to characterize potential exposures to chemicals of current and emerging concern. The PRoTEGE system has been implemented for ambient and indoor environments, utilizing available MNP production, usage, and properties databases, along with laboratory measurements of potential personal exposures from consumer spray products containing nAg. Modeling of environmental and microenvironmental levels of MNPs employs Probabilistic Material Flow Analysis combined with product LCA to account for releases during manufacturing, transport, usage, disposal, etc. Human exposure and dose characterization further employs screening Microenvironmental Modeling and Intake Fraction methods combined with LSA for potentially exposed populations, to assess differences associated with gender, age, and demographics. Population distributions of intakes, estimated using the PRoTEGE framework, are consistent with published individual-based intake estimates, demonstrating that PRoTEGE is capable of capturing realistic exposure scenarios for the US population. Distributions of intakes are also used to calculate biologically-relevant population distributions of uptakes and target tissue doses through human airway dosimetry modeling that takes into account product MNP size distributions and age-relevant physiological parameters.

Indexed as

consumer productsengineered nanomaterialslife cycle analysislife stage analysismanufactured nanoparticlesPRoTEGEsilver nanoparticles

Identifiers

PMID25745354
PMCPMC4346165

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.