ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2015
Exercise compliance among patients with multiple myeloma undergoing chemotherapy: a retrospective study.
Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 3 of them syntheses that pooled it.
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Who cites it
15 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.
- Safety, feasibility, and effectiveness of exercise interventions in patients with hematologic malignancy during chemotherapy: a systematic review and meta-analysis.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025Pooled it
- The effect of exercise interventions on quality of life in patients with multiple myeloma: a systematic review and meta-analysis of randomised controlled trials.Clinical and experimental medicine · 2023Pooled it
- Mobilization and Exercise Intervention for Patients With Multiple Myeloma: Clinical Practice Guidelines Endorsed by the Canadian Physiotherapy Association.Physical therapy · 2021Guideline
- Exercise for myeloma patients with bone disease: a scoping review.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026Article
- Risk Stratification Strategies and Implementation of Exercise Training in Patients with Multiple Myeloma.Current oncology reports · 2025Review
- Perceptions of Older Adults with Hematological Cancer on Diet and Exercise Behavior and Its Role in Navigating Daily Tasks.International journal of environmental research and public health · 2022Article
- Clinical exercise therapy program with multiple myeloma patients: Impacts on feasibility, adherence and efficacy.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2022Article
- Physical Activity and Cancer Care-A Review.Cancers · 2022Review
- Feasibility of implementing an exercise intervention in older adults with hematologic malignancy.Journal of geriatric oncology · 2022Article
- Physical Activity in People with Multiple Myeloma: Associated Factors and Exercise Program Preferences.Journal of clinical medicine · 2020Article
- Effect of an Inpatient Rehabilitation Program for Recovery of Deconditioning in Hematologic Cancer Patients After Chemotherapy.Annals of rehabilitation medicine · 2018Article
- Article
- Rehabilitation and exercise oncology program: translating research into a model of care.Current oncology (Toronto, Ont.) · 2017Article
- Physical exercise modulates the level of serum MMP-2 and MMP-9 in patients with breast cancer.Oncology letters · 2016Article
- Article
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeMultiple myeloma (MM) is often associated with osteolytic bone disease and anemia, resulting in skeletal fragility and persistent fatigue, pain, and reduced quality of life. Exercise is considered safe and beneficial for this population. Our objectives were to evaluate the extent to which MM patients undergoing chemotherapy complied with exercise recommendations and to identify factors associated with noncompliance.
methodsThis retrospective study included 41 MM patients referred to a hospital-based rehabilitation program while undergoing chemotherapy. Variables collected at baseline (T1) and follow-up (T2) included: (a) demographics and medical history, (b) exercise levels (MET-hours/week), preferences and barriers, and (c) fatigue severity scores (0-10). Statistical analyses included logistic regression to identify factors associated with exercise noncompliance and t-tests and chi-squared tests to compare outcomes between the groups according to compliance.
resultsThe mean age of the participants was 61 years; 73 % were male and 81 % had bone lesions. Overall exercise compliance at T2 was 71 %, with an observed increase in exercise levels (mean group difference: 6.5 MET-hours/week; p < 0.001) and decrease in fatigue severity scores (mean group difference -1.2; p = 0.003). Factors associated with exercise noncompliance included history of pathological fracture (odds ratio [OR] 4.7; p = 0.049), spinal cord compression (SCC) (OR 14.1; p = 0.023), and radiation (OR 28.0; p < 0.001).
conclusionsIn this sample of MM patients, high compliance with exercise and associated improvements in fatigue were observed. However, participants with a history of pathological fracture, SCC, or radiation are at increased risk of noncompliance and may require additional supervision to improve exercise compliance.
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