ArticleScientific reports2015
Paper and flexible substrates as materials for biosensing platforms to detect multiple biotargets.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 58 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
58 citing papers in PubMed.
- Multiplex solid-phase RPA coupled CRISPR-based visual detection of SARS-CoV-2.Biosensors & bioelectronics: X · 2023Article
- Recent Advances in Colorimetric Tests for the Detection of Infectious Diseases and Antimicrobial Resistance.Diagnostics (Basel, Switzerland) · 2023Review
- Aptamer-Based Point-of-Care Devices: Emerging Technologies and Integration of Computational Methods.Biosensors · 2023Review
- Effective Optical Image Assessment of Cellulose Paper Immunostrips for Blood Typing.International journal of molecular sciences · 2022Article
- Diagnostic assay and technology advancement for detecting SARS-CoV-2 infections causing the COVID-19 pandemic.Analytical and bioanalytical chemistry · 2022Review
- Paper and thread as media for the frugal detection of urinary tract infections (UTIs).Analytical and bioanalytical chemistry · 2022Review
- Development of a Microfluidic Device for CD4Biosensors · 2021Article
- Nano-functionalized paper-based IoT enabled devices for point-of-care testing: a review.Biomedical microdevices · 2021Review
- Dengue Detection: Advances in Diagnostic Tools from Conventional Technology to Point of Care.Biosensors · 2021Review
- Development of a Point-of-Care Assay for HIV-1 Viral Load Using Higher Refractive Index Antibody-Coated Microbeads.Sensors (Basel, Switzerland) · 2021Article
- Lysis and direct detection of coliforms on printed paper-based microfluidic devices.Lab on a chip · 2020Article
- Review
- Nanomaterial-mediated paper-based biosensors for colorimetric pathogen detection.Trends in analytical chemistry : TRAC · 2020Review
- Detection of Bacterial and Viral Pathogens Using Photonic Point-of-Care Devices.Diagnostics (Basel, Switzerland) · 2020Review
- CytoPAN-Portable cellular analyses for rapid point-of-care cancer diagnosis.Science translational medicine · 2020Article
- Article
- Magnetic Particles: Their Applications from Sample Preparations to Biosensing Platforms.Micromachines · 2020Review
- Flexible potentiometric pH sensors for wearable systems.RSC advances · 2020Review
- Development of a multiplex fully automated assay for rapid quantification of CD4Biosensors & bioelectronics · 2019Article
- A review on advances in methods for modification of paper supports for use in point-of-care testing.Mikrochimica acta · 2019Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
Abstract
The need for sensitive, robust, portable, and inexpensive biosensing platforms is of significant interest in clinical applications for disease diagnosis and treatment monitoring at the point-of-care (POC) settings. Rapid, accurate POC diagnostic assays play a crucial role in developing countries, where there are limited laboratory infrastructure, trained personnel, and financial support. However, current diagnostic assays commonly require long assay time, sophisticated infrastructure and expensive reagents that are not compatible with resource-constrained settings. Although paper and flexible material-based platform technologies provide alternative approaches to develop POC diagnostic assays for broad applications in medicine, they have technical challenges integrating to different detection modalities. Here, we address the limited capability of current paper and flexible material-based platforms by integrating cellulose paper and flexible polyester films as diagnostic biosensing materials with various detection modalities through the development and validation of new widely applicable electrical and optical sensing mechanisms using antibodies and peptides. By incorporating these different detection modalities, we present selective and accurate capture and detection of multiple biotargets including viruses (Human Immunodeficiency Virus-1), bacteria (Escherichia coli and Staphylococcus aureus), and cells (CD4(+) T lymphocytes) from fingerprick volume equivalent of multiple biological specimens such as whole blood, plasma, and peritoneal dialysis effluent with clinically relevant detection and sensitivity.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.