Evidence map›Paper›PMID 25743468›Full record

ArticleScientific reports2015

Microrheology with optical tweezers: measuring the relative viscosity of solutions 'at a glance'.

Manlio Tassieri, Francesco Del Giudice, Emma J Robertson, Neena Jain, Bettina Fries, Rab Wilson, Andrew Glidle, Francesco Greco, Paolo Antonio Netti, Pier Luca Maffettone and 2 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. TheMaterials today. Bio · 2026
    Review
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  3. Article
  4. Review
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
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  13. Microrheology reveals microscale viscosity gradients in planktonic systems.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  14. Review
  15. Article
  16. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Manlio TassieriDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow G12 8LT, UK.
Francesco Del GiudiceCenter for Advanced Biomaterials for Health Care @CRIB, IIT, P.le Tecchio 80, 80125 Naples, Italy.
Emma J RobertsonDepartment of Infection and Immunity, St George's University of London, London SW17 0RS, UK.
Neena JainDepartment of Medicine, Albert Einstein College of Medicine, Bronx NY, USA.
Bettina FriesDepartment of Medicine, Albert Einstein College of Medicine, Bronx NY, USA.
Rab WilsonDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow G12 8LT, UK.
Andrew GlidleDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow G12 8LT, UK.
Francesco GrecoIstituto di Ricerche sulla Combustione, IRC-CNR, P.le Tecchio 80, 80125 Naples, Italy.
Paolo Antonio NettiCenter for Advanced Biomaterials for Health Care @CRIB, IIT, P.le Tecchio 80, 80125 Naples, Italy.
Pier Luca MaffettoneDipartimento di Ingegneria Chimica, dei Materiali e della Produzione Industriale, , Universitá di Napoli Federico II, P.le Tecchio 80, 80125 Naples, Italy.
Tihana BicanicDepartment of Infection and Immunity, St George's University of London, London SW17 0RS, UK.
Jonathan M CooperDivision of Biomedical Engineering, School of Engineering, University of Glasgow, Glasgow G12 8LT, UK.

Funding

response to phenotypic switch variants to C. neoformansR01AI059681 · NIAID · STATE UNIVERSITY NEW YORK STONY BROOK · PI FRIES, BETTINA · 2004 to 2014
$3.6M
NIAID NIH HHS R01 AI059681Wellcome TrustWellcome Trust WT 089966
6 · The paper itself

Abstract

We present a straightforward method for measuring the relative viscosity of fluids via a simple graphical analysis of the normalised position autocorrelation function of an optically trapped bead, without the need of embarking on laborious calculations. The advantages of the proposed microrheology method are evident when it is adopted for measurements of materials whose availability is limited, such as those involved in biological studies. The method has been validated by direct comparison with conventional bulk rheology methods, and has been applied both to characterise synthetic linear polyelectrolytes solutions and to study biomedical samples.

Indexed as

Optical TweezersRheologySolutionsViscositySolutions

Identifiers

PMID25743468
PMCPMC4894396

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.