Evidence map›Paper›PMID 25742749›Full record

ArticleLeukemia2015

Notch-mediated expansion of cord blood progenitors: maintenance of transcriptional and epigenetic fidelity.

A Dahlberg, S Woo, C Delaney, P Boyle, A Gnirke, C Bock, B E Bernstein, A Meissner, R Gottardo, I D Bernstein

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Leukemia, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

A DahlbergPediatric Oncology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
S WooPS Statistics, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
C DelaneyPediatric Oncology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
P BoyleBroad Institute of MIT and Harvard, Cambridge, MA, USA.
A GnirkeBroad Institute of MIT and Harvard, Cambridge, MA, USA.
C BockBroad Institute of MIT and Harvard, Cambridge, MA, USA.ORCID http://orcid.org/0000-0001-6091-3088
B E BernsteinBroad Institute of MIT and Harvard, Cambridge, MA, USA.
A MeissnerBroad Institute of MIT and Harvard, Cambridge, MA, USA.
R GottardoPS Statistics, Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.
I D BernsteinPediatric Oncology, Clinical Research Division, Fred Hutchinson Cancer Research Center, Seattle, WA, USA.

Funding

Translational Bioimaging Core Shared ResourceP30CA015704 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Marian Esvelt · 1985 to 2026
$296.4M
CAREER DEVELOPMENT IN PEDIATRIC AND MEDICAL ONCOLOGYK12CA076930 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI DAVIDSON, NANCY ELLEN, MESHINCHI, SOHEIL · 1997 to 2025
$13.1M
Expansion of Cardiac and Hematopoietic Pregenitors by Wnt and NotchU01HL100395 · NHLBI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BERNSTEIN, IRWIN D, MOON, RANDALL TODD · 2009 to 2015
$8.4M
PEDIATRIC ONCOLOGY RESEARCH TRAINING PROGRAMT32CA009351 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI Elizabeth R Lawlor, SOHEIL MESHINCHI · 1985 to 2026
$7.0M
NCI NIH HHS K12 CA076930NCI NIH HHS K12CA076930NCI NIH HHS P30 CA015704NCI NIH HHS T32 CA009351NCI NIH HHS T32CA009351NHLBI NIH HHS U01 HL100395NHLBI NIH HHS U01HL100395
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsEpigenesis, GeneticFetal BloodGene Expression RegulationHematopoietic Stem CellsHumansMiceReceptors, NotchTranscription, GeneticReceptors, Notch

Identifiers

PMID25742749
PMCPMC4558340

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.