Evidence map›Paper›PMID 25742714›Full record

ReviewVirology2015

Bacteriophage lambda: Early pioneer and still relevant.

Sherwood R Casjens, Roger W Hendrix

Open access · greenAbstract readHistorical ArticleReview
In one paragraph

Review in Virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 173 papers.

0numbers the graph read from it
0cells of the map it votes in
173citing papers in PubMed
18.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

173 citing papers in PubMed, 341 citations in OpenAlex.

  1. Revisiting the life cycle of temperate phages.Nature reviews. Microbiology · 2026
    Review
  2. Counting to two: how phages decide between lysis and lysogeny.bioRxiv : the preprint server for biology · 2026
    Article
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Observational
  13. Discovery and characterization of a novelPHAGE (New Rochelle, N.Y.) · 2026
    Article
  14. Article
  15. Article
  16. Article
  17. Article
  18. Structural basis for Lamassu-based antiviral immunity and its evolution from DNA repair machinery.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  19. Article
  20. Article

113 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Sherwood R CasjensDivision of Microbiology and Immunology, Pathology Department, University of Utah School of Medicine, Emma Eccles Jones Medical Research Building, 15 North Medical Drive East, Salt Lake City, UT 84112, USA; Biology Department, University of Utah, Salt Lake City, UT 84112, USA. Electronic address: sherwood.casjens@path.utah.edu.
Roger W HendrixDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, PA 15260, USA.
University of Pittsburgh · USUniversity of Utah · US

Funding

ASSEMBLY AND STRUCTURE OF BACTERIOPHAGE LAMBDAR01GM047795 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DUDA, ROBERT LOUIS · 1991 to 2017
$7.8M
DNA packaging and delivery by dsDNA virusesR01GM114817 · NIGMS · UNIVERSITY OF UTAH · PI CASJENS, SHERWOOD R. · 2014 to 2017
$1.5M
NIGMS NIH HHS GM114817NIGMS NIH HHS GM47795NIGMS NIH HHS R01 GM047795NIGMS NIH HHS R01 GM114817
6 · The paper itself

Abstract

Molecular genetic research on bacteriophage lambda carried out during its golden age from the mid-1950s to mid-1980s was critically important in the attainment of our current understanding of the sophisticated and complex mechanisms by which the expression of genes is controlled, of DNA virus assembly and of the molecular nature of lysogeny. The development of molecular cloning techniques, ironically instigated largely by phage lambda researchers, allowed many phage workers to switch their efforts to other biological systems. Nonetheless, since that time the ongoing study of lambda and its relatives has continued to give important new insights. In this review we give some relevant early history and describe recent developments in understanding the molecular biology of lambda's life cycle.

Indexed as

Bacteriophage lambdaHistory, 20th CenturyHistory, 21st CenturyMolecular BiologyBacteriophageLambdaLambdoid phages

Identifiers

PMID25742714
PMCPMC4424060
OpenAlexW2034840813

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.