ArticlePLoS pathogens2015
Is antigenic sin always "original?" Re-examining the evidence regarding circulation of a human H1 influenza virus immediately prior to the 1918 Spanish flu.
Article in PLoS pathogens, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Mathematical Modeling of Influenza Dynamics: Integrating Seasonality and Gradual Waning Immunity.Bulletin of mathematical biology · 2025Article
- The health and demographic impacts of the "Russian flu" pandemic in Switzerland in 1889/1890 and in the years thereafter.Epidemiology and infection · 2024Article
- Pre-existing immunity to influenza aids ferrets in developing stronger and broader H3 vaccine-induced antibody responses.Vaccine · 2024Article
- Article
- An Unwanted but Long-Known Company: Post-Viral Symptoms in the Context of Past Pandemics in Switzerland (and Beyond).Public health reviews · 2024Review
- Immune imprinting and next-generation coronavirus vaccines.Nature microbiology · 2023Review
- Immunological imprinting of humoral immunity to SARS-CoV-2 in children.Nature communications · 2023Article
- Racial Disparities in Mortality During the 1918 Influenza Pandemic in United States Cities.Demography · 2022Article
- Neutralizing Antibody Response toViruses · 2022Article
- Personality Traits, Risk Perception, and Protective Behaviors of Arab Residents of Qatar During the COVID-19 Pandemic.International journal of mental health and addiction · 2022Article
- Influenza immune escape under heterogeneous host immune histories.Trends in microbiology · 2021Review
- Centenarians exposed to the Spanish flu in their early life better survived to COVID-19.Aging · 2021Article
- Determinants of Influenza Mortality Trends: Age-Period-Cohort Analysis of Influenza Mortality in the United States, 1959-2016.Demography · 2019Article
- The 1918 Influenza Pandemic: Looking Back, Looking Forward.American journal of epidemiology · 2018Article
- Article
- Article
- Anti-neuraminidase antibodies against pandemic A/H1N1 influenza viruses in healthy and influenza-infected individuals.PloS one · 2018Article
- Influenza, evolution, and the next pandemic.Evolution, medicine, and public health · 2018Review
- From Original Antigenic Sin to the Universal Influenza Virus Vaccine.Trends in immunology · 2018Review
- The role of human immunity and social behavior in shaping influenza evolution.PLoS pathogens · 2017Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PubMed holds no abstract for this paper.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.