Evidence map›Paper›PMID 25742455›Full record

ArticleNature medicine2015

Toward recreating colon cancer in human organoids.

Ameen A Salahudeen, Calvin J Kuo

Abstract readComment
PubMed Publisher
In one paragraph

Article in Nature medicine, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
1.3field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 22 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Review
  5. Article
  6. Review
  7. Article
  8. Article
  9. Organ-on-a-Chip for Cancer and Immune Organs Modeling.Advanced healthcare materials · 2019
    Review
  10. Article
  11. Insights into the role of the intestinal microbiota in colon cancer.Therapeutic advances in gastroenterology · 2017
    Review
  12. Article
  13. Article
  14. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Ameen A SalahudeenDepartment of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, USA.
Calvin J KuoDepartment of Medicine, Division of Hematology, Stanford University School of Medicine, Stanford, California, USA.
Stanford University · US

Funding

Regulation of actively proliferating and quiescent intestinal stem cellsU01DK085527 · NIDDK · STANFORD UNIVERSITY · PI KUO, CALVIN J · 2009 to 2023
$6.9M
Intestinal Stem Cell Consortium Coordinating CenterU01DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2009 to 2018
$6.5M
Functional Analysis of Oncogenic Networks in Primary OrganoidsU01CA176299 · NCI · STANFORD UNIVERSITY · PI JI, HANLEE P, KUO, CALVIN J · 2013 to 2016
$3.6M
Integrated Genomic Discovery and Functional Validation of Colorectal Cancer LociU01CA151920 · NCI · STANFORD UNIVERSITY · PI JI, HANLEE P, KUO, CALVIN J · 2011 to 2015
$2.6M
Limited Competition for the Continuation of the Intestinal Stem Cell Consortium Coordinating CenterU24DK085532 · NIDDK · BECKMAN RESEARCH INSTITUTE/CITY OF HOPE · PI NILAND, JOYCE CAROL · 2019 to 2023
$2.3M
NCI NIH HHS U01 CA151920NCI NIH HHS U01 CA176299NIDDK NIH HHS U01 DK085527NIDDK NIH HHS U01 DK085532NIDDK NIH HHS U24 DK085532
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Gene Expression Regulation, NeoplasticIntestinal MucosaOrganoidsAdenocarcinomaAdenomaAnimalsColorectal NeoplasmsHumans

Identifiers

PMID25742455
OpenAlexW2007095592

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.