ArticlePloS one2015
Association between low-grade albuminuria and cardiovascular risk in Korean adults: the 2011-2012 Korea National Health and Nutrition Examination Survey.
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Acarbose Reduces Low-Grade Albuminuria Compared to Metformin in Chinese Patients with Newly Diagnosed Type 2 Diabetes.Diabetes, metabolic syndrome and obesity : targets and therapy · 2021Trial
- Article
- Low-grade albuminuria and its relationship with cardiovascular disease risk in hypertensive and diabetic patients in primary health care.BMC nephrology · 2022Article
- Comparing Multiple Linear Regression and Machine Learning in Predicting Diabetic Urine Albumin-Creatinine Ratio in a 4-Year Follow-Up Study.Journal of clinical medicine · 2022Article
- The association between albuminuria and thyroid antibodies in newly diagnosed type 2 diabetes mellitus patients with Hashimoto's thyroiditis and euthyroidism.BMC endocrine disorders · 2020Article
- Metformin or Acarbose Treatment Significantly Reduced Albuminuria in Patients with Newly Diagnosed Type 2 Diabetes Mellitus and Low-Grade Albuminuria.Medical science monitor : international medical journal of experimental and clinical research · 2018Article
- Association between low-grade albuminuria and frailty among community-dwelling middle-aged and older people: a cross-sectional analysis from I-Lan Longitudinal Aging Study.Scientific reports · 2016Article
- Urinary Albumin Excretion Reflects Cardiovascular Risk in Postmenopausal Women without Diabetes: The 2011 to 2013 Korean National Health and Nutrition Examination Survey.Endocrinology and metabolism (Seoul, Korea) · 2016Article
- Estimated glomerular filtration rate and albuminuria in Korean population evaluated for cardiovascular risk.International urology and nephrology · 2016Article
- Albuminuria Is Associated with Open-Angle Glaucoma in Nondiabetic Korean Subjects: A Cross-Sectional Study.PloS one · 2016Article
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6 authors.
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Abstract
backgroundRecent studies have indicated that low UACR levels (<30 μg/mg) previously considered to be in the normal range ('low-grade albuminuria') are associated with cardiovascular morbidity and mortality in the general population.
methodsWe studied 9,736 participants with albuminuria in the normal range from the 2011-2012 Korea National Health and Nutrition Examination Survey (KNHANES).
resultsThe weighted prevalences of metabolic syndrome (MS) and the 10-year risk for coronary heart disease measured using the Framingham risk score (FRS) ≥ 20% (high risk) were 22.5 ± 0.7% and 14.5 ± 0.7%, respectively, in males and 23.3 ± 0.8% and 8.5 ± 0.4%, respectively in females. Weighted comparisons among the tertiles of UACR revealed that the prevalences of MS and high-risk FRS increased with increasing UACR (MS: males, 15.9 ± 1.1, 20.2 ± 1.2, 32.4 ± 1.5%, respectively; P < 0.001; and females, 17.6 ± 1.0, 22.7 ± 1.0, 30.2 ± 1.4%, respectively; P < 0.001. High-risk FRS: males, 9.5 ± 0.7, 12.3 ± 0.9, 22.5 ± 1.2, respectively; P < 0.001; and females, 5.8 ± 0.6, 7.9 ± 0.7, 12.0 ± 0.9%, respectively; P < 0.001). The positive association persisted after adjusting for hypertension and diabetes. The weighted comparisons among the deciles of UACR revealed that the prevalences of MS and high-risk FRS began to increase at the ranges of 3.89-5.15 and 5.16-7.36 mg/g Cr, respectively.
conclusionLow-grade albuminuria was significantly associated with estimated cardiovascular risk and MS in a nationally representative sample of Koreans.
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