Observational studyChest2015
Mechanical Ventilation and ARDS in the ED: A Multicenter, Observational, Prospective, Cross-sectional Study.
Observational study in Chest, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01628523 (Mechanical Ventilation in the Emergency Department), which is not on this map. Cited by 36 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Mechanical Ventilation in the Emergency Department: A Prospective Cross-Sectional Study
Who cites it
36 citing papers in PubMed, 74 citations in OpenAlex.
- Assessment of mortality risk by respiratory rate-specific quartiles in mechanically ventilated patients with acute respiratory distress syndrome in Mexico.Internal and emergency medicine · 2026Observational
- Management of Mechanical Ventilation in Emergency Medicine: A Scoping Review.Journal of the American College of Emergency Physicians open · 2026Review
- Disparities Exist in the Application of Low Tidal-volume Ventilation in the Emergency Department.The western journal of emergency medicine · 2023Observational
- Acute Respiratory Distress Syndrome.Emergency medicine clinics of North America · 2022Review
- A dual-center cohort study on the association between early deep sedation and clinical outcomes in mechanically ventilated patients during the COVID-19 pandemic: The COVID-SED study.Critical care (London, England) · 2022Article
- Mechanical Ventilation Practices and Low Tidal Volume Ventilation in Air Medical Transport Patients: The AIR-VENT Study.Respiratory care · 2022Article
- A Dual-Center Cohort Study on The Association Between Early Deep Sedation and Clinical Outcomes in Mechanically Ventilated Patients During the COVID-19 Pandemic: the COVID-SED Study.Research square · 2022Article
- Initiation of a Lung Protective Ventilation Strategy in the Emergency Department: Does an Emergency Department-Based ICU Make a Difference?Critical care explorations · 2022Article
- Association of ROX Index with Mechanical Ventilator Use in Sepsis Patients in the Emergency Department.Journal of clinical medicine · 2022Article
- Quality Improvement Intervention associated with Improved Lung Protective Ventilation Settings in an Emergency Department.Spartan medical research journal · 2022Article
- A Target for Increased Mortality Risk in Critically Ill Patients: The Concept of Perpetuity.Journal of clinical medicine · 2021Article
- Implementation of an ED-based bundled mechanical ventilation protocol improves adherence to lung-protective ventilation.The American journal of emergency medicine · 2021Observational
- The ED-AWARENESS Study: A Prospective, Observational Cohort Study of Awareness With Paralysis in Mechanically Ventilated Patients Admitted From the Emergency Department.Annals of emergency medicine · 2021Observational
- An Emergency Amendment to the National Scope of Practice for Paramedics in the Setting of a Global Pandemic.The Journal of rural health : official journal of the American Rural Health Association and the National Rural Health Care Association · 2021Article
- Article
- Observational
- The effect of emergency department crowding on lung-protective ventilation utilization for critically ill patients.Journal of critical care · 2019Observational
- Mechanical Ventilation Training During Graduate Medical Education: Perspectives and Review of the Literature.Journal of graduate medical education · 2019Review
- Article
- Prospective Assessment of the Feasibility of a Trial of Low-Tidal Volume Ventilation for Patients with Acute Respiratory Failure.Annals of the American Thoracic Society · 2019Observational
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors at 8 institutions in 1 country.
Funding
Abstract
backgroundThere are few data regarding mechanical ventilation and ARDS in the ED. This could be a vital arena for prevention and treatment.
methodsThis study was a multicenter, observational, prospective, cohort study aimed at analyzing ventilation practices in the ED. The primary outcome was the incidence of ARDS after admission. Multivariable logistic regression was used to determine the predictors of ARDS.
resultsWe analyzed 219 patients receiving mechanical ventilation to assess ED ventilation practices. Median tidal volume was 7.6 mL/kg predicted body weight (PBW) (interquartile range, 6.9-8.9), with a range of 4.3 to 12.2 mL/kg PBW. Lung-protective ventilation was used in 122 patients (55.7%). The incidence of ARDS after admission from the ED was 14.7%, with a mean onset of 2.3 days. Progression to ARDS was associated with higher illness severity and intubation in the prehospital environment or transferring facility. Of the 15 patients with ARDS in the ED (6.8%), lung-protective ventilation was used in seven (46.7%). Patients who progressed to ARDS experienced greater duration in organ failure and ICU length of stay and higher mortality.
conclusionsLung-protective ventilation is infrequent in patients receiving mechanical ventilation in the ED, regardless of ARDS status. Progression to ARDS is common after admission, occurs early, and worsens outcome. Patient- and treatment-related factors present in the ED are associated with ARDS. Given the limited treatment options for ARDS, and the early onset after admission from the ED, measures to prevent onset and to mitigate severity should be instituted in the ED. TRIAL REGISTRY: ClinicalTrials.gov; No.: NCT01628523; URL: www.clinicaltrials.gov.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.