ArticleJournal of pediatric endocrinology & metabolism : JPEM2015
Rickets and vitamin D deficiency in Alaska native children.
Article in Journal of pediatric endocrinology & metabolism : JPEM, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 1 of them a synthesis that pooled it.
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Who cites it
21 citing papers in PubMed, 1 synthesis or guideline pooled it, 51 citations in OpenAlex.
- Vitamin D level and fractures in children and adolescents: a systematic review and meta-analysis.Journal of bone and mineral metabolism · 2021Pooled it
- Early life nutrition in Nunavut, Canada: a retrospective descriptive study of food security, vitamin D and rickets.International journal of circumpolar health · 2025Article
- Dietary Micronutrient Intake and the Prevalence of Metabolic Conditions among Children from the United States-Affiliated Pacific Region in the Children's Healthy Living Program.Current developments in nutrition · 2025Article
- Key recommendations and research priorities of the 2021 AMAP human health assessment.International journal of circumpolar health · 2024Article
- Increased ENaC-mediated liquid absorption across vitamin-D deficient human airway epithelia.American journal of physiology. Cell physiology · 2024Article
- Physical Activity, Sleep, and Demographic Patterns in Alaska Native Children and Youth Living in Anaktuvuk Pass.Youth (Basel, Switzerland) · 2023Article
- Article
- Vitamin D, rickets and child abuse: controversies and evidence.Pediatric radiology · 2021Review
- Comparison of Vitamin D and 25-Hydroxyvitamin D Concentrations in Human Breast Milk between 1989 and 2016-2017.Nutrients · 2021Article
- Adherence to Vitamin D Intake Guidelines in the United States.Pediatrics · 2020Article
- One health in the circumpolar North.International journal of circumpolar health · 2019Article
- A closer look at rickets and vitamin D deficiency in Manitoba: The tip of the iceberg.Paediatrics & child health · 2019Article
- Association of Maternal Vitamin D Deficiency with Early Childhood Caries.Journal of dental research · 2019Article
- Biochemical parameters of rickets in Iranian children: A systematic review and meta-analysis.Journal of research in medical sciences : the official journal of Isfahan University of Medical Sciences · 2019Review
- Responsible Research With Urban American Indians and Alaska Natives.American journal of public health · 2018Review
- Nutritional Rickets Presenting as Chronic Episodic Extremity Pain in a 9-year-old with Autism.Clinical practice and cases in emergency medicine · 2018Article
- Declines in traditional marine food intake and vitamin D levels from the 1960s to present in young Alaska Native women.Public health nutrition · 2017Article
- Prevalence of vitamin D deficiency and its association with nutrition, travelling and clothing habits in an immigrant population in Northern Sweden.European journal of clinical nutrition · 2016Article
- Genetics, Diet, and Season Are Associated with Serum 25-Hydroxycholecalciferol Concentration in a Yup'ik Study Population from Southwestern Alaska.The Journal of nutrition · 2016Article
- Etiology and Biochemical Profile of Rickets in Tertiary Care Centres in Eastern India: A Retrospective Cross-sectional Study.Indian journal of endocrinology and metabolismArticle
Corrections and comments
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Authors and funding
12 authors at 4 institutions in 1 country.
Funding
Abstract
backgroundRickets and vitamin D deficiency appeared to increase in Alaskan children starting in the 1990s. We evaluated the epidemiology of rickets and vitamin D deficiency in Alaska native (AN) children in 2001-2010.
methodsWe analyzed 2001-2010 visits with rickets or vitamin D deficiency diagnosis for AN and American Indian children and the general US population aged <10 years. We conducted a case-control study of AN rickets/vitamin D deficient cases and age- and region-matched controls.
resultsIn AN children, annual rickets-associated hospitalization rate (2.23/100,000 children/year) was higher than the general US rate (1.23; 95% CI 1.08-1.39). Rickets incidence increased with latitude. Rickets/vitamin D deficiency cases were more likely to have malnutrition (OR 38.1; 95% CI 4.9-294), had similar breast-feeding prevalence, and were less likely to have received vitamin D supplementation (OR 0.23; 95% CI 0.1-0.87) than controls.
conclusionsOur findings highlight the importance of latitude, malnutrition, and lack of vitamin D supplementation as risk factors for rickets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.