ArticleJournal of biomedical optics2015
Structure tensor analysis of serial optical coherence scanner images for mapping fiber orientations and tractography in the brain.
Article in Journal of biomedical optics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Bridging the microstructural gap in human connectomics using hierarchical phase-contrast tomography as a reference for diffusion MRI in the human brain.bioRxiv : the preprint server for biology · 2026Article
- What needs to be standardized for reliable, reproducible, and robust tractography?GigaScience · 2026Review
- The modular nature of long-association pathways in the human brain.bioRxiv : the preprint server for biology · 2026Article
- Reconstructing the human brain's wiring diagram from axons up.Trends in neurosciences · 2026Review
- Micron-resolution fiber mapping in histology independent of sample preparation.Nature communications · 2025Article
- Validation of structure tensor analysis for orientation estimation in brain tissue microscopy.Journal of neuroscience methods · 2025Article
- Micron-resolution fiber mapping in histology independent of sample preparation.bioRxiv : the preprint server for biology · 2025Article
- Catheter-based polarimetric imaging to complement MRI for deep brain stimulation neurosurgery.Neurophotonics · 2025Article
- Validation of Structure Tensor Analysis for Orientation Estimation in Brain Tissue Microscopy.bioRxiv : the preprint server for biology · 2025Article
- Three-dimensional fiber orientation mapping of ex vivo human brain at micrometer resolution.Npj imaging · 2025Article
- Multi-Scale Label-Free Human Brain Imaging with Integrated Serial Sectioning Polarization Sensitive Optical Coherence Tomography and Two-Photon Microscopy.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2023Article
- Using light and X-ray scattering to untangle complex neuronal orientations and validate diffusion MRI.eLife · 2023Article
- Posttraumatic Stress and Traumatic Brain Injury: Cognition, Behavior, and Neuroimaging Markers in Vietnam Veterans.Journal of Alzheimer's disease : JAD · 2023Article
- The influence of regions of interest on tractography virtual dissection protocols: general principles to learn and to follow.Brain structure & function · 2022Article
- High-fidelity approximation of grid- and shell-based sampling schemes from undersampled DSI using compressed sensing: Post mortem validation.NeuroImage · 2021Article
- Synchrotron X-ray micro-CT as a validation dataset for diffusion MRI in whole mouse brain.Magnetic resonance in medicine · 2021Article
- Scattered Light Imaging: Resolving the substructure of nerve fiber crossings in whole brain sections with micrometer resolution.NeuroImage · 2021Article
- Comparison of diffusion MRI and CLARITY fiber orientation estimates in both gray and white matter regions of human and primate brain.NeuroImage · 2021Article
- Whole Murine Brain Imaging Based on Optical Elastic Scattering.Advances in experimental medicine and biology · 2021Article
- Challenges for biophysical modeling of microstructure.Journal of neuroscience methods · 2020Review
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3 authors.
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Abstract
Quantitative investigations of fiber orientation and structural connectivity at microscopic resolution have led to great challenges for current neuroimaging techniques. Here, we present a structure tensor (ST) analysis of ex vivo rat brain images acquired by a multicontrast (MC) serial optical coherence scanner. The ST considers the gradients of images in local neighbors to generate a matrix whose eigen-decomposition can estimate the local features such as the edges, anisotropy, and orientation of tissue constituents. This computational analysis is applied on the conventional- and polarization-based contrasts of optical coherence tomography. The three-dimensional (3-D) fiber orientation maps are computed from the image stacks of sequential scans both at mesoresolution for a global view and at high-resolution for the details. The computational orientation maps demonstrate a good agreement with the optic axis orientation contrast which measures the in-plane fiber orientation. Moreover, tractography is implemented using the directional information extracted from the 3-D ST. The study provides a unique opportunity to leverage MC high-resolution information to map structural connectivity of the whole brain.
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