ArticleInternational journal of environmental research and public health2015
Association of PNC, BC, and PM2.5 measured at a central monitoring site with blood pressure in a predominantly near highway population.
Article in International journal of environmental research and public health, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 54 citations in OpenAlex.
- A systematic review of cardiovascular responses associated with ambient black carbon and fine particulate matter.Environment international · 2019Pooled it
- Health effects of ultrafine particles: a systematic literature review update of epidemiological evidence.International journal of public health · 2019Pooled it
- Ambient Ultrafine Particles and Hypertensive Disorders of Pregnancy: A Mediation Analysis of Homocysteine in a Birth Cohort.Environment & health (Washington, D.C.) · 2026Article
- Short- and Long-Term Effects of Inhaled Ultrafine Particles on Blood Pressure: A Systematic Review and Meta-Analysis.Journal of clinical medicine · 2024Review
- Air pollution and blood pressure in the elderly: evidence from a panel study in Nanjing, China.Heliyon · 2022Article
- Short-Term Cumulative Exposure to Ambient Traffic-Related Black Carbon and Blood Pressure: MMDA Traffic Enforcers' Health Study.International journal of environmental research and public health · 2021Article
- Ultrafine Particle Number Concentration Model for Estimating Retrospective and Prospective Long-Term Ambient Exposures in Urban Neighborhoods.Environmental science & technology · 2020Article
- Unraveling the blood transcriptome after real-life exposure of Wistar-rats to PM2.5, PM1 and water-soluble metals in the ambient air.Toxicology reports · 2020Article
- Synthesis of Harvard Environmental Protection Agency (EPA) Center studies on traffic-related particulate pollution and cardiovascular outcomes in the Greater Boston Area.Journal of the Air & Waste Management Association (1995) · 2019Article
- Wearable Ultrafine Particle and Noise Monitoring Sensors Jointly Measure Personal Co-Exposures in a Pediatric Population.International journal of environmental research and public health · 2019Article
- Long-Term Exposure to Ultrafine Particles and Incidence of Cardiovascular and Cerebrovascular Disease in a Prospective Study of a Dutch Cohort.Environmental health perspectives · 2018Article
- Short-and medium-term associations of particle number concentration with cardiovascular markers in a Puerto Rican cohort.Environmental research · 2018Article
- Relationship of Time-Activity-Adjusted Particle Number Concentration with Blood Pressure.International journal of environmental research and public health · 2018Article
- The value of using seasonality and meteorological variables to model intra-urban PMAtmospheric environment (Oxford, England : 1994) · 2018Article
- Longitudinal associations of long-term exposure to ultrafine particles with blood pressure and systemic inflammation in Puerto Rican adults.Environmental health : a global access science source · 2018Article
- Association of Long-Term Near-Highway Exposure to Ultrafine Particles with Cardiovascular Diseases, Diabetes and Hypertension.International journal of environmental research and public health · 2017Article
- Particulate Matter Exposure in a Police Station Located near a Highway.International journal of environmental research and public health · 2015Article
Corrections and comments
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Authors and funding
8 authors at 3 institutions in 2 countries.
Funding
Abstract
Elevated blood pressure is an indicator of cardiovascular stress and increased risk of cardiovascular-related morbidity and mortality. There is emerging evidence suggesting air pollutants, including particulate matter (PM), could promote hypertension, thereby increasing cardiovascular disease risk. Repeated measurement analyses were conducted to examine the associations of three types of PM with systolic blood pressure (SBP), diastolic blood pressure (DBP), and pulse pressure (PP) in 220 participants, (mean age=58.5 years) from the Community Assessment of Freeway Exposure and Health study (CAFEH), most of whom live near a major highway. Ambient levels of air pollutants including particle number concentration (PNC; a measure of ultrafine particle (UFP) concentration), fine PM (PM2.5, Particle diameter<2.5 µm), and black carbon (BC) were measured at a central site<7 km from the study areas. Central sites are good at capturing short-term temporal trends in pollution associated with meteorological changes over regional areas. Linear mixed-effect models that accounted for repeated measures within one person were used to examine the associations between blood pressure variables and daily average of ambient PNC, PM2.5, or BC, controlling for demographic characteristics and major confounders including temperature. Our PNC model predicted that a higher PNC of 10,000 particles/cm3 was associated with higher DBP of 2.40 mmHg (p=0.03), independent of other factors in the model. There were no significant associations for PM2.5 or BC. Post hoc subgroup analyses by obesity status showed that positive associations of DBP with PNC were more pronounced among obese individuals than non-obese individuals. These results suggested that PNC levels are associated with increased blood pressure, which may contribute to cardiovascular disease risk. More research is needed to assess the relationship between PNC and blood pressure and to address possible residual confounding.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.