Evidence map›Paper›PMID 25741602›Full record

ArticleNanotechnology2015

Dielectrophoretic stretching of DNA tethered to a fiber tip.

Changbae Hyun, Harpreet Kaur, David S McNabb, Jiali Li

Abstract read
In one paragraph

Article in Nanotechnology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 11 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Changbae HyunDepartment of Physics, University of Arkansas, Fayetteville AR 72701, USA.
Harpreet KaurDepartment of Physics, University of Arkansas, Fayetteville AR 72701, USA.
David S McNabbDepartment of Biological Sciences, University of Arkansas, Fayetteville AR 72701, USA.
Jiali LiDepartment of Physics, University of Arkansas, Fayetteville AR 72701, USA.
University of Arkansas at Fayetteville · US

Funding

Exploration of Solid-state Nanopore Reading Labeled Linear DNA SequenceR21HG004776 · NHGRI · UNIVERSITY OF ARKANSAS AT FAYETTEVILLE · PI LI, JIALI · 2008 to 2012
$1.0M
NHGRI NIH HHS R21 HG004776NHGRI NIH HHS R21HG004776
6 · The paper itself

Abstract

In this work, we studied the stretching of λ phage DNA molecules immobilized on an optical fiber tip attached to a force sensitive tuning fork under ac electric fields. We designed a two electrodes stretching system in a small chamber: one is a gold-coated optical fiber tip electrode, and the other is a gold-coated flat electrode. By applying a dielectrophoretic (DEP) force, the immobilized λ DNA molecules on the tip are stretched and the stretching process is monitored by a fluorescent microscope. The DNA stretching in three-dimensional space is optimized by varying electrode shape, electrode gap distance, ac frequency, and solution conductivity. By observing the vibrational amplitude change of a quartz tuning fork, we measured the effects due to Joule heating and the DEP force on the tethered DNA molecules in solution. This work demonstrates a method to manipulate and characterize immobilized λ DNA molecules on a probe tip for further study of single DNA molecules.

Indexed as

Electromagnetic PhenomenaOptical FibersOptical TweezersAnimalsBacteriophage lambdaComputer SimulationDNAElectrodesGoldHumansDNAGold

Identifiers

PMID25741602
PMCPMC4411638
OpenAlexW2067597407

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.