Evidence map›Paper›PMID 25741389›Full record

ArticleAir quality, atmosphere, & health2012

Air pollution and health: emerging information on susceptible populations.

Marie S O'Neill, Carrie V Breton, Robert B Devlin, Mark J Utell

Abstract read
In one paragraph

Article in Air quality, atmosphere, & health, 2012. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 3 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Article
  5. Article
  6. Article
  7. Review
  8. Particulate Air Pollution Exposure and Stroke among Adults in Israel.International journal of environmental research and public health · 2023
    Article
  9. Postnatal exposure to PMEnvironmental epidemiology (Philadelphia, Pa.) · 2022
    Article
  10. Article
  11. Article
  12. Article
  13. Personal NOInternational journal of environmental research and public health · 2019
    Article
  14. Article
  15. Article
  16. Article
  17. Disease and Health Inequalities Attributable to Air Pollutant Exposure in Detroit, Michigan.International journal of environmental research and public health · 2017
    Article
  18. Respiratory Effects and Systemic Stress Response Following Acute Acrolein Inhalation in Rats.Toxicological sciences : an official journal of the Society of Toxicology · 2017
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Marie S O'NeillSchool of Public Health, University of Michigan, 6631 SPH Tower, 109 South Observatory, Ann Arbor, MI 48109-2029, USA.
Carrie V BretonDepartment of Preventive Medicine, Keck School of Medicine, University of Southern California, 1540 Alcazar St. CHP 236, Los Angeles, CA 90033, USA.
Robert B DevlinClinical Research Branch, Environmental Public Health Division, U.S. Environmental Protection Agency, 104 Mason Farm Road, Chapel Hill, NC 27599-7315, USA.
Mark J UtellDepartment of Medicine, University of Rochester Medical Center, Box EHSC, 575 Elmwood Avenue, Rochester, NY 14642, USA. Department of Environmental Medicine, University of Rochester Medical Center, Box EHSC, 575 Elmwood Avenue, Rochester, NY 14642, USA.

Funding

Translational Research Support CoreP30ES007048 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ROB S MCCONNELL · 1996 to 2026
$46.4M
Urban Air Pollution &Persistent Early Life AsthmaP01ES009581 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI GILLILAND, FRANK D. · 1999 to 2010
$6.8M
Air Pollution, Inflammation and Preterm Birth: A Mechanistic Study in Mexico CityR01ES016932 · NIEHS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI O'NEILL, MARIE SYLVIA · 2008 to 2015
$2.2M
Prenatal air pollution, DNA methylation and early signs of atherosclerosisK01ES017801 · NIEHS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BRETON, CARRIE VAN DOREN · 2010 to 2014
$652k
NIEHS NIH HHS K01 ES017801NIEHS NIH HHS P01 ES009581NIEHS NIH HHS P30 ES007048NIEHS NIH HHS R01 ES016932
6 · The paper itself

Abstract

Outdoor air pollution poses risks to human health in communities around the world, and research on populations who are most susceptible continues to reveal new insights. Human susceptibility to adverse health effects from exposure to air pollution can be related to underlying disease; demographic or anthropometric characteristics; genetic profile; race and ethnicity; lifestyle, behaviors, and socioeconomic position; and location of residence or daily activities. In health research, an individual or group may have an enhanced responsiveness to a given, identical level of pollution exposure compared to those who are less susceptible. Or, people in these different groups may experience varying levels of exposure (for example, a theoretically homogeneous population whose members differ only by proximity to a road). Often the information available for health research may relate to both exposure and enhanced response to a given dose of pollution. This paper discusses the general direction of research on susceptibility to air pollution, with a general though not an exclusive focus on particulate matter, with specific examples of research on susceptibility related to cardiovascular disease, diabetes, asthma, and genetic and epigenetic features. We conclude by commenting how emerging knowledge of susceptibility can inform policy for controlling pollution sources and exposures to yield maximal health benefit and discuss two areas of emerging interest: studying air pollution and its connection to perinatal health, as well as land use and urban infrastructure design.

Indexed as

DiabetesGeneticsOutdoor airParticulate matterSusceptible populations

Identifiers

PMID25741389
PMCPMC4345419

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.