Evidence map›Paper›PMID 25741195›Full record

ArticleKorean journal of radiology

Qualitative and quantitative analysis with contrast-enhanced ultrasonography: diagnosis value in hypoechoic renal angiomyolipoma.

Qing Lu, Bei-jian Huang, Wen-ping Wang, Cui-xian Li, Li-yun Xue

Open access · hybridAbstract read
In one paragraph

Article in Korean journal of radiology. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.

  1. Pooled it
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  11. What's new in urologic ultrasound?Indian journal of urology : IJU : journal of the Urological Society of India
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Qing LuShanghai Imaging Institute of Medicine, Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Bei-jian HuangShanghai Imaging Institute of Medicine, Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Wen-ping WangShanghai Imaging Institute of Medicine, Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Cui-xian LiShanghai Imaging Institute of Medicine, Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Li-yun XueShanghai Imaging Institute of Medicine, Department of Ultrasound, Zhongshan Hospital, Fudan University, Shanghai 200032, China.
Fudan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo evaluate the value of enhancement features and quantitative parameters of contrast-enhanced ultrasonography (CEUS) in differentiating solid hypoechoic renal angiomyolipomas (AMLs) from clear cell renal cell carcinomas (ccRCCs). MATERIALS AND

methodsWe analyzed the enhancement features and quantitative parameters of CEUS in 174 hypoechoic renal masses (32 AMLs and 142 ccRCCs) included in the study.

resultsCentripetal enhancement pattern was more common in AMLs than in ccRCCs on CEUS (71.9% vs. 23.2%, p < 0.001). At peak enhancement, all AMLs showed homogeneous enhancement (100% in AML, 27.5% in ccRCCs; p < 0.001). Quantitative analysis showed no significant difference between rise time and time to peak. Tumor-to-cortex (TOC) enhancement ratio in AMLs was significantly lower than that in ccRCCs (p < 0.001). The criteria of centripetal enhancement and homogeneous peak enhancement together with TOC ratio < 91.0% used to differentiate hypoechoic AMLs from ccRCCs resulted in a sensitivity and specificity of 68.9% and 95.8%, respectively.

conclusionBoth qualitative and quantitative analysis with CEUS are valuable in the differential diagnosis of hypoechoic renal AMLs from ccRCCs.

Indexed as

AdultAgedAngiomyolipomaCarcinoma, Renal CellContrast MediaDiagnosis, DifferentialFemaleHumansKidney NeoplasmsLanguageLipomaMaleMiddle AgedSensitivity and SpecificityUltrasonographyContrast MediaAngiomyolipomaContrast-enhanced ultrasonographyMinimal fatQuantitative analysisRenal cell carcinoma

Identifiers

PMID25741195
PMCPMC4347269
OpenAlexW2124525721

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.