ArticleHeart (British Cardiac Society)2015
Stress resilience and physical fitness in adolescence and risk of coronary heart disease in middle age.
Article in Heart (British Cardiac Society), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.
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Who cites it
32 citing papers in PubMed, 1 synthesis or guideline pooled it, 68 citations in OpenAlex.
- Psychological Resilience, Cardiovascular Disease, and Metabolic Disturbances: A Systematic Review.Frontiers in psychology · 2022Pooled it
- Peripubertal pregnancies and associations with health and developmental outcomes in offspring during late adolescence and adulthood: sibling-comparison register study.International journal of epidemiology · 2026Article
- Development and validation of risk factors lifestyle disorders scale (RFLDS): A cohort study.Dialogues in health · 2026Article
- Social network characteristics, self-management behavior, and the mediating role of self-efficacy among diabetes patients: a multicenter cross-sectional study.Frontiers in endocrinology · 2026Article
- Stress Resilience and Risk of Psychiatric Disorders After Childhood Bereavement.JAMA network open · 2025Article
- Resilience, Survival, and Functional Independence in Older Adults Facing Critical Illness.Chest · 2024Article
- Psychological resilience to lifetime trauma and risk for cardiometabolic disease and mortality in older adults: A longitudinal cohort study.Journal of psychosomatic research · 2023Article
- Roles of alcohol use disorder and resilience in risk of suicide attempt in men: A Swedish population-based cohort.Suicide & life-threatening behavior · 2022Article
- Spiritual Well-Being and Its Association with Coronary Artery Disease.Journal of religion and health · 2022Article
- Resilience Is Associated with Less Eating Disorder Symptoms in the NutriNet-Santé Cohort Study.International journal of environmental research and public health · 2022Article
- Association of Psychological Resilience with All-Cause and Cardiovascular Mortality in a General Population in Italy: Prospective Findings from the Moli-Sani Study.International journal of environmental research and public health · 2021Article
- Timing, duration, and differential susceptibility to early life adversities and cardiovascular disease risk across the lifespan: Implications for future research.Preventive medicine · 2021Review
- Association of Innate and Acquired Aerobic Capacity With Resilience in Healthy Adults: Protocol for a Randomized Controlled Trial of an 8-Week Web-Based Physical Exercise Intervention.JMIR research protocols · 2021Article
- Psychological and biological resilience modulates the effects of stress on epigenetic aging.Translational psychiatry · 2021Article
- Psychological resilience predicting cardiometabolic conditions in adulthood in the Midlife in the United States Study.Proceedings of the National Academy of Sciences of the United States of America · 2021Article
- Greater Neurobiological Resilience to Chronic Socioeconomic or Environmental Stressors Associates With Lower Risk for Cardiovascular Disease Events.Circulation. Cardiovascular imaging · 2020Observational
- Associations between social network properties and metabolic syndrome and the mediating effect of physical activity: findings from the Cardiovascular and Metabolic Diseases Etiology Research Center (CMERC) Cohort.BMJ open diabetes research & care · 2020Article
- Association between resilience and a functional polymorphism in the serotonin transporter (SLC6A4) gene: A meta-analysis.EXCLI journal · 2020Article
- Shared unmeasured characteristics among siblings confound the association of Apgar score with stress resilience in adolescence.Acta paediatrica (Oslo, Norway : 1992) · 2019Article
- Stress resilience in young men mediates the effect of childhood trauma on their offspring's birth weight - An analysis of 250,000 families.SSM - population health · 2019Article
Corrections and comments
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Authors and funding
5 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivePsychosocial stress is a suggested risk for coronary heart disease (CHD). The relationship of stress resilience in adolescence with subsequent CHD risk is underinvestigated, so our objective was to assess this and investigate the possible mediating role of physical fitness.
methodsIn this register-based study, 237,980 men born between 1952 and 1956 were followed from 1987 to 2010 using information from Swedish registers. Stress resilience was measured at a compulsory military conscription examination using a semistructured interview with a psychologist. Some 10,581 diagnoses of CHD were identified. Cox regression estimated the association of stress resilience with CHD, with adjustment for established cardiovascular risk factors.
resultsLow-stress resilience was associated with increased CHD risk. The association remained after adjustment for physical fitness and other potential confounding and mediating factors, with adjusted HRs (and 95% CIs) of 1.17 (1.10 to 1.25), with some evidence of mediation by physical fitness. CHD incidence rates per 1000 person-years (and 95% CIs) for low-stress, medium-stress and high-stress resilience were 2.61 (2.52 to 2.70), 1.97 (1.92 to 2.03) and 1.59 (1.53 to 1.67) respectively. Higher physical fitness was inversely associated with CHD risk; however, this was attenuated by low-stress resilience, shown by interaction testing (p < 0.001).
conclusionsLow-stress resilience in adolescence was associated with increased risk of CHD in middle age and may diminish the benefit of physical fitness. This represents new evidence of the role of stress resilience in determining risk of CHD and its interrelationship with physical fitness.
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