Evidence map›Paper›PMID 25740721›Full record

ArticleThe Enzymes

Structure and Function of the ZTL/FKF1/LKP2 Group Proteins in Arabidopsis.

Brian D Zoltowski, Takato Imaizumi

Abstract read
In one paragraph

Article in The Enzymes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed.

  1. Review
  2. The Kelch-Repeat Superfamily GenePlants (Basel, Switzerland) · 2026
    Article
  3. Review
  4. Review
  5. Steady-stateFrontiers in plant science · 2026
    Article
  6. Article
  7. Review
  8. Environmental conditions and nutritional quality of vegetables in protected cultivation.Comprehensive reviews in food science and food safety · 2025
    Review
  9. Article
  10. Functional Characterization of thePlants (Basel, Switzerland) · 2024
    Article
  11. Light signaling as cellular integrator of multiple environmental cues in plants.Physiology and molecular biology of plants : an international journal of functional plant biology · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Transcriptome sequencing and global analysis of blue light-responsive genes provide clues for high carotenoid yields in Blakeslea trispora.International microbiology : the official journal of the Spanish Society for Microbiology · 2022
    Article
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Brian D ZoltowskiDepartment of Chemistry, Southern Methodist University, Dallas, Texas, USA. Electronic address: bzoltowski@mail.smu.edu.
Takato ImaizumiDepartment of Biology, University of Washington, Seattle, Washington, USA. Electronic address: takato@u.washington.edu.

Funding

Molecular Mechanisms of Seasonal Time MeasurementR01GM079712 · NIGMS · UNIVERSITY OF WASHINGTON · PI IMAIZUMI, TAKATO · 2007 to 2022
$3.5M
NIGMS NIH HHS R01 GM079712
6 · The paper itself

Abstract

The ZTL/FKF1/LKP2 group proteins are LOV-domain-based blue-light photoreceptors that control protein degradation by ubiquitination. These proteins were identified relatively recently and are known to be involved in the regulation of the circadian clock and photoperiodic flowering in Arabidopsis. In this review, we focus on two topics. First, we summarize the molecular mechanisms by which ZTL and FKF1 regulate these biological phenomena based on genetic and biochemical analyses. Next, we discuss the chemical properties of the ZTL family LOV domains obtained from structural, biophysical, and photochemical characterizations of the LOV domains. These two different levels of approach unveiled the molecular mechanisms by which plants utilize ZTL and FKF1 proteins to monitor light for daily and seasonal adaptation.

Indexed as

ArabidopsisBlue-light photoreceptorCircadian clockF-boxFKF1FlavinLKP2LOV domainPhotocyclePhotoperiodismProtein degradationProtein–protein interactionZTL

Identifiers

PMID25740721
PMCPMC4348042

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.