Evidence map›Paper›PMID 25740329›Full record

ArticleDisease models & mechanisms2015

Early loss of ambulation is not a representative clinical feature in Duchenne muscular dystrophy dogs: remarks on the article of Barthélémy et al.

Dongsheng Duan, Chady H Hakim, Carlos E Ambrosio, Bruce F Smith, H Lee Sweeney

Open access · goldAbstract readLetterComment
PubMed Full text at PMC Publisher
In one paragraph

Article in Disease models & mechanisms, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 6 citations in OpenAlex.

  1. Canine Model of Duchenne Muscular Dystrophy.Methods in molecular biology (Clifton, N.J.) · 2026
    Article
  2. Current Pharmacological Strategies for Duchenne Muscular Dystrophy.Frontiers in cell and developmental biology · 2021
    Review
  3. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 4 institutions in 2 countries.

Dongsheng DuanDepartment of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO 65212, USA Department of Neurology, School of Medicine, The University of Missouri, Columbia, MO 65212, USA duand@missouri.edu.
Chady H HakimDepartment of Molecular Microbiology and Immunology, School of Medicine, The University of Missouri, Columbia, MO 65212, USA.
Carlos E AmbrosioDepartment of Veterinary Medicine, Faculty of Animal Science and Food Engineering, University of São Paulo, Pirassununga 05508-070, Brazil.
Bruce F SmithScott-Ritchey Research Center, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA Department of Pathobiology, College of Veterinary Medicine, Auburn University, Auburn, AL 36849, USA.
H Lee SweeneyDepartment of Physiology, School of Medicine, The University of Pennsylvania, Philadelphia, PA 19104, USA.
University of Missouri · USAuburn University · USUniversidade de São Paulo · BRUniversity of Pennsylvania · US

Funding

Whole body single AAV microgene therapy in canine DMDR01NS090634 · NINDS · UNIVERSITY OF MISSOURI-COLUMBIA · PI Dongsheng Duan · 2015 to 2026
$4.2M
Dual AAV Vectors for Duchenne Muscular Dystrophy TherapyR01AR049419 · NIAMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DUAN, DONGSHENG · 2003 to 2012
$4.1M
Treatment of Duchenne Muscular Dystrophy with the Muscle Calcium PumpR01AR070517 · NIAMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DUAN, DONGSHENG · 2016 to 2020
$3.1M
Duchenne Cardiomyopathy Gene TherapyR01HL091883 · NHLBI · UNIVERSITY OF MISSOURI-COLUMBIA · PI DUAN, DONGSHENG · 2010 to 2013
$2.0M
Exploring systemic AAV gene delivery in the dystrophic dogR21AR057209 · NIAMS · UNIVERSITY OF MISSOURI-COLUMBIA · PI DUAN, DONGSHENG · 2008 to 2009
$372k
NHLBI NIH HHS HL-91883NHLBI NIH HHS R01 HL091883NIAMS NIH HHS AR057209NIAMS NIH HHS AR-49419NIAMS NIH HHS R01 AR049419NIAMS NIH HHS R01 AR070517NIAMS NIH HHS R21 AR057209NINDS NIH HHS R01 NS090634
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Disease Models, AnimalAnimalsBiomarkersMuscular Dystrophy, DuchenneBiomarkers

Identifiers

PMID25740329
PMCPMC4348558
OpenAlexW2161530712

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.