ArticleEuropean spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society2015
Impaired bone mineral density as a predictor of graft subsidence following minimally invasive transpsoas lateral lumbar interbody fusion.
Article in European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 66 papers, 4 of them syntheses that pooled it.
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Who cites it
66 citing papers in PubMed, 4 syntheses or guidelines pooled it, 151 citations in OpenAlex.
- Single level versus multi-level lumbar interbody fusion for lumbar degenerative diseases: a systematic review and meta analysis.Journal of orthopaedic surgery and research · 2026Pooled it
- Oblique lumbar interbody fusion versus posterior lumbar interbody fusion for adjacent segment disease following prior lumbar fusion: a meta-analysis.Journal of orthopaedic surgery and research · 2025Pooled it
- Defining cage subsidence in anterior, oblique, and lateral lumbar spine fusion approaches: a systematic review of the literature.Neurosurgical review · 2024Pooled it
- Influence of the geometric and material properties of lumbar endplate on lumbar interbody fusion failure: a systematic review.Journal of orthopaedic surgery and research · 2022Pooled it
- Stand-alone prone lateral interbody fusion: a retrospective case series.Journal of spine surgery (Hong Kong) · 2026Article
- Mini-incision oblique lumbar interbody fusion (OLIF) and anterolateral screw-rod fixation for surgical treatment of L5 spondylolisthesis.Annals of medicine and surgery (2012) · 2026Article
- Impact of Expandable versus Static Interbody Cages on Subsidence and Outcomes in Minimally Invasive Transforaminal Lumbar Interbody Fusion: A Systematic Review and Meta-Analysis.Global spine journal · 2026Review
- Quantitative CT-Derived Volumetric Bone Mineral Density Threshold for Predicting Cage Subsidence After Oblique Lumbar Interbody Fusion.Tomography (Ann Arbor, Mich.) · 2026Article
- Comparison of clinical efficacy between endoscope-assisted oblique lumbar interbody fusion and posterior lumbar interbody fusion in the treatment of lumbar degenerative diseases.Frontiers in surgery · 2026Article
- Use of Double Cages for Biportal Endoscopic Transforaminal Lumbar Interbody Fusion: A Comparison of 3-Dimensional-Printed Titanium and Polyetheretherketone Cages.International journal of spine surgery · 2025Article
- Clinical efficacy of robotZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025Article
- An in vitro biomechanical evaluation of integrated lateral plate combined with oblique lateral interbody fusion in different bone conditions.Scientific reports · 2024Article
- Assessment of factors implicated in bone fusion after percutaneous endoscopic lumbar intervertebral fusion.Acta orthopaedica et traumatologica turcica · 2024Article
- Are the facet joint parameters risk factors for cage subsidence after TLIF in patients with lumbar degenerative spondylolisthesis?European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2024Article
- Injectable bone cement cannulated pedicle screw for lumbar degenerative disease in osteoporosis - clinical follow-up of over 5 years.Journal of orthopaedic surgery and research · 2024Article
- Myth or fact: 3D-printed off-the-shelf prosthesis is superior to titanium mesh cage in anterior cervical corpectomy and fusion?BMC musculoskeletal disorders · 2024Article
- Factors associated with intervertebral cage subsidence in posterior lumbar fusion.Journal of orthopaedic surgery and research · 2024Article
- Article
- Risk factors for low back pain after oblique lumbar interbody fusion in patients with low-grade degenerative lumbar spondylolisthesis: a retrospective study.Frontiers in surgery · 2024Article
- Cortical Endplate Bone Density Measured by Novel Phantomless Quantitative Computed Tomography May Predict Cage Subsidence more Conveniently and Accurately.Orthopaedic surgery · 2023Article
6 more citing papers are in PubMed but not listed here.
Corrections and comments
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Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThe LLIF procedure is a useful stand-alone and adjunct surgical approach for many spinal conditions. One complication of LLIF is subsidence of the interbody graft into the vertebral bodies, resulting in severe pain, impaired arthrodesis and potentially fracture of the body. Low bone density, as measured by T score on DEXA scanning, has also been postulated to increase the risk of subsidence.
methodsA retrospective review of prospectively collected data was performed on all patients who underwent LLIF at this institution consisting of 712 levels in 335 patients. Patients with subsidence following LLIF were recorded. We utilized the T score obtained from the femoral neck DEXA scans, which is used to determine overall fracture risk. The T score of patients with subsidence was compared to those without subsidence.
results20 of 57 (35 %) patients without subsidence had a DEXA T score between -1.0 and -2.4 consistent osteopenia, one patient (1.8 %) exhibited a T score less than -2.5, consistent with osteoporosis. 13 patients of 23 (57 %) with subsidence exhibited a T score between -1.0 and -2.4, consistent with osteopenia, five (22 %) exhibited a T score of -2.5 or less, consistent with osteoporosis. The mean DEXA T score in patients with subsidence was -1.65 (SD 1.04) compared to -0.45 (SD 0.97) in patients without subsidence (p < 0.01). The area under the receiver operating characteristic curve for patients with a T score of -1.0 or less was 80.1 %.
conclusionsPatients with DEXA T scores less than -1.0 who undergo stand-alone LLIF are at a much higher risk of developing graft subsidence. Further, they are at an increased risk of requiring additional surgery. In patients with poor bone quality, consideration could be made to supplement the LLIF cage with posterior instrumentation.
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