Evidence map›Paper›PMID 25739382›Full record

Trial reportInternational journal of hematology2015

Analysis of clinical characteristics and prognostic factors for angioimmunoblastic T-cell lymphoma.

Yoshihiro Kameoka, Naoto Takahashi, Shigeki Itou, Masaaki Kume, Hideyoshi Noji, Yuichi Kato, Yoshikazu Ichikawa, Osamu Sasaki, Mutsuhito Motegi, Atsushi Ishiguro and 6 more

Abstract readClinical TrialMulticenter Study
PubMed Publisher
In one paragraph

Trial report in International journal of hematology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
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  12. T-cell lymphomas, a challenging disease: types, treatments, and future.International journal of clinical oncology · 2017
    Review
  13. Article
  14. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 9 institutions in 1 country.

Yoshihiro KameokaDepartment of Hematology, Akita University, Akita, Japan, ykameoka@doc.med.akita-u.ac.jp.
Naoto Takahashi
Shigeki Itou
Masaaki Kume
Hideyoshi Noji
Yuichi Kato
Yoshikazu Ichikawa
Osamu Sasaki
Mutsuhito Motegi
Atsushi Ishiguro
Hiroyuki Tagawa
Kenichi Ishizawa
Yoji Ishida
Ryo Ichinohasama
Hideo Harigae
Kenichi Sawada
Akita University · JPTohoku University · JPIwate Medical University · JPAkita University Hospital · JPFukushima Medical University · JPHiraka General Hospital · JPHirosaki University · JPMiyagi Prefectural Hospital Organization · JPYamagata University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Angioimmunoblastic T-cell lymphoma (AITL) is a distinct peripheral T-cell lymphoma entity exhibiting peculiar clinical features and poor prognosis. Its clinical characteristics and prognostic factors are not well established. To clarify the clinical characteristics and prognostic features of AITL, we conducted a multicenter, retrospective study. Fifty-six patients were enrolled. The median patient age was 68 years. Immunohistochemical examinations of tumor cells showed positivity for CD10 and T-cell markers, and chromosomal examination detected several types of abnormalities. More than 80 % of patients show advanced disease at diagnosis and poor prognostic scores. A high proportion of patients showed accompanying B symptoms, splenomegaly, and hepatomegaly at diagnosis. The 5-year overall survival (OS) rate was 48 % and progression-free survival was 25 %. Univariate analysis revealed higher age, fever, poor performance status, anemia, and low albumin level to be poor prognostic factors for OS. In addition to these factors, both IPI and PIT were also predictive of OS. Multivariate analysis indicated only a low level of serum albumin to be a significant prognostic factor for OS. Serum albumin may be one of the important prognostic factors for AITL. Further investigation is needed to confirm these results.

Indexed as

AdultAgedAged, 80 and overAntineoplastic Combined Chemotherapy ProtocolsDisease-Free SurvivalFemaleHumansLymphoma, T-Cell, PeripheralMaleMiddle AgedMultivariate AnalysisPrognosisRetrospective StudiesSerum AlbuminStem Cell TransplantationTreatment OutcomeSerum Albumin

Identifiers

PMID25739382
OpenAlexW2027364993

What OpenQuestion holds

Textmetadata
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.