SynthesisScientific reports2015
Dietary legume consumption reduces risk of colorectal cancer: evidence from a meta-analysis of cohort studies.
Synthesis in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 43 papers, 11 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
43 citing papers in PubMed, 11 syntheses or guidelines pooled it.
- National and subnational incidence, mortality and associated factors of colorectal cancer in China: A systematic analysis and modelling study.Journal of global health · 2023Pooled it
- Legume Consumption and Risk of All-Cause and Cause-Specific Mortality: A Systematic Review and Dose-Response Meta-Analysis of Prospective Studies.Advances in nutrition (Bethesda, Md.) · 2023Pooled it
- Nuts and legumes consumption and risk of colorectal cancer: a systematic review and meta-analysis.European journal of epidemiology · 2022Pooled it
- Do Common Beans (Nutrients · 2021Pooled it
- Consumption of red meat and processed meat and cancer incidence: a systematic review and meta-analysis of prospective studies.European journal of epidemiology · 2021Pooled it
- Role of Diet in Colorectal Cancer Incidence: Umbrella Review of Meta-analyses of Prospective Observational Studies.JAMA network open · 2021Pooled it
- Pooled it
- Mediterranean Diet Pyramid: A Proposal for Italian People. A Systematic Review of Prospective Studies to Derive Serving Sizes.Nutrients · 2019Pooled it
- Dietary Inflammatory Index and Site-Specific Cancer Risk: A Systematic Review and Dose-Response Meta-Analysis.Advances in nutrition (Bethesda, Md.) · 2018Pooled it
- Legume intake and risk of prostate cancer: a meta-analysis of prospective cohort studies.Oncotarget · 2017Pooled it
- Meta-analysis of Soy Consumption and Gastrointestinal Cancer Risk.Scientific reports · 2017Pooled it
- Plasma and Urine Metabolite Profiles Impacted by Increased Dietary Navy Bean Intake in Colorectal Cancer Survivors: A Randomized-Controlled Trial.Cancer prevention research (Philadelphia, Pa.) · 2021Trial
- Metabolomics Based Biomarkers of Green Beans Intake.Molecular nutrition & food research · 2026Article
- Article
- Legume Consumption in Relation to Ulcerative Colitis: A Case-Control Study.Current therapeutic research, clinical and experimental · 2026Article
- Article
- Association Between EGFR Expression in Non-Small Cell Lung Cancer and Dietary Legume Intake.Current drug targets · 2026Article
- Dietary Fiber Intake Was Inversely Associated with All-Cause Mortality but Not with Cancer and Cardiovascular Disease Mortalities in the US.Diseases (Basel, Switzerland) · 2025Article
- The Relevance of Sex and Age as Non-Modifiable Risk Factors in Relation to Clinical-Pathological Parameters in Colorectal Cancer.Life (Basel, Switzerland) · 2025Article
- Legume intake and cancer risk in a network of case-control studies.European journal of clinical nutrition · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Previous epidemiological studies on the relation between dietary legume consumption and risk of colorectal cancer (CRC) remain controversial. We conducted a meta-analysis based on prospective cohort studies to investigate the association between dietary legume consumption and risk of CRC. Fourteen cohort studies were finally included, containing a total of 1,903,459 participants and 12,261 cases who contributed 11,628,960 person-years. We found that higher legume consumption was associated with a decreased risk of CRC (RR, relative risk = 0.91; 95% CI, confidence interval = 0.84-0.98). Subgroup analyses suggested that higher legume consumption was inversely associated with CRC risk in Asian (RR = 0.82; 95% CI = 0.74-0.91) and soybean intake was associated with a decreased risk of CRC (RR = 0.85; 95% CI = 0.73-0.99). Findings from our meta-analysis supported an association between higher intake of legume and a reduced risk of CRC. Further studies controlled for appropriate confounders are warranted to validate the associations.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.