ArticlePloS one2015
Transcriptomic analysis reveals differential gene expressions for cell growth and functional secondary metabolites in induced autotetraploid of Chinese woad (Isatis indigotica Fort.).
Article in PloS one, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Phenotypic and Metabolic Variations Induced by Autopolyploidization in Chinese Jujube Cultivars.Plants (Basel, Switzerland) · 2025Article
- Medicinal Plants with Potential Inhibitory Bioactive Compounds against Coronaviruses.Advanced pharmaceutical bulletin · 2022Review
- Transcriptome and proteome analysis suggest enhanced photosynthesis in tetraploid Liriodendron sino-americanum.Tree physiology · 2021Article
- Integrative analyses of targeted metabolome and transcriptome of Isatidis Radix autotetraploids highlighted key polyploidization-responsive regulators.BMC genomics · 2021Article
- Multiple responses contribute to the enhanced drought tolerance of the autotetraploid Ziziphus jujuba Mill. var. spinosa.Cell & bioscience · 2021Article
- Whole-Genome Doubling Affects Pre-miRNA Expression in Plants.Plants (Basel, Switzerland) · 2021Article
- Genome Size Covaries More Positively with Propagule Size than Adult Size: New Insights into an Old Problem.Biology · 2021Article
- Integrated Analysis of Metabolome and Transcriptome Reveals Insights for Cold Tolerance in Rapeseed (Frontiers in plant science · 2021Article
- Article
- Investigation of genes associated with petal variations between diploid and autotetraploid in Chinese cabbage (Brassica rapa L. ssp. pekinensis) by RNA-seq and sRNA-seq.Molecular genetics and genomics : MGG · 2020Article
- Cross-Species Annotation of Expressed Genes and Detection of Different Functional Gene Modules Between 10 Cold- and 10 Hot-Propertied Chinese Herbal Medicines.Frontiers in genetics · 2020Article
- Synthetic Polyploidy in Grafted Crops.Frontiers in plant science · 2020Review
- Molecular basis underlying the successful invasion of hexaploid cytotypes ofEcology and evolution · 2019Article
- Changes in endogenous phytohormones regulated by microRNA-target mRNAs contribute to the development of Dwarf Autotetraploid Chinese Cabbage (Brassica rapa L. ssp. pekinensis).Molecular genetics and genomics : MGG · 2018Article
- Comparison of leaf transcriptomes of cassava "Xinxuan 048" diploid and autotetraploid plants.Genes & genomics · 2018Article
- Article
- Transcriptome analysis of neo-tetraploid rice reveals specific differential gene expressions associated with fertility and heterosis.Scientific reports · 2017Article
- Phenotypic and Comparative Transcriptome Analysis of Different Ploidy Plants inFrontiers in plant science · 2017Article
- Selection and Validation of Appropriate Reference Genes for qRT-PCR Analysis inFrontiers in plant science · 2017Article
- Implications of polyploidy events on the phenotype, microstructure, and proteome of Paulownia australis.PloS one · 2017Article
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6 authors.
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Abstract
The giant organs and enhanced concentrations of secondary metabolites realized by autopolyploidy are attractive for breeding the respective medicinal and agricultural plants and studying the genetic mechanisms. The traditional medicinal plant Chinese woad (Isatis indigotica Fort., 2n = 2x = 14) is now still largely used for the diseases caused by bacteria and viruses in China. In this study, its autopolyploids (3x, 4x) were produced and characterized together with the 2x donor for their phenotype and transcriptomic alterations by using high-throughput RNA sequencing. With the increase of genome dosage, the giantism in cells and organs was obvious and the photosynthetic rate was higher. The 4x plants showed predominantly the normal meiotic chromosome pairing (bivalents and quadrivalents) and equal segregation and then produced the majority of 4x progeny. The total 70136 All-unigenes were de novo assembled, and 56,482 (80.53%) unigenes were annotated based on BLASTx searches of the public databases. From pair-wise comparisons between transcriptomic data of 2x, 3x, 4x plants, 1856 (2.65%)(2x vs 4x), 693(0.98%)(2x vs 3x), 1045(1.48%)(3x vs 4x) unigenes were detected to differentially expressed genes (DEGs), including both up- and down-regulated ones. These DEGs were mainly involved in cell growth (synthesis of expansin and pectin), cell wall organization, secondary metabolite biosynthesis, response to stress and photosynthetic pathways. The up-regulation of some DEGs for metabolic pathways of functional compounds in the induced autotetraploids substantiates the promising new type of this medicinal plant with the increased biomass and targeted metabolites.
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