Evidence map›Paper›PMID 25738860›Full record

ArticleBiomacromolecules2015

Synthesis of multifunctional cellulose nanocrystals for lectin recognition and bacterial imaging.

Juan Zhou, Núria Butchosa, H Surangi N Jayawardena, JaeHyeung Park, Qi Zhou, Mingdi Yan, Olof Ramström

Abstract read
In one paragraph

Article in Biomacromolecules, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Quantification of binding affinity of glyconanomaterials with lectins.Chemical communications (Cambridge, England) · 2020
    Review
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Review
  12. Glyconanomaterials for biosensing applications.Biosensors & bioelectronics · 2016
    Review
  13. Glyconanomaterials for Combating Bacterial Infections.Chemistry (Weinheim an der Bergstrasse, Germany) · 2015
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Juan Zhou
Núria Butchosa
H Surangi N Jayawardena§Department of Chemistry, University of Massachusetts-Lowell, 1 University Avenue, Lowell, Massachusetts 01854, United States.
JaeHyeung Park§Department of Chemistry, University of Massachusetts-Lowell, 1 University Avenue, Lowell, Massachusetts 01854, United States.
Qi Zhou⊥School of Biotechnology, AlbaNova University Center, KTH - Royal Institute of Technology, S-10691 Stockholm, Sweden.
Mingdi Yan§Department of Chemistry, University of Massachusetts-Lowell, 1 University Avenue, Lowell, Massachusetts 01854, United States.
Olof Ramström

Funding

Photogenerated Carbohydrate MicroarraysR01GM080295 · NIGMS · UNIVERSITY OF MASSACHUSETTS LOWELL · PI YAN, MINGDI · 2008 to 2012
$2.0M
NIGMS NIH HHS R01 GM080295NIGMS NIH HHS R01GM080295
6 · The paper itself

Abstract

Multifunctional cellulose nanocrystals have been synthesized and applied as a new type of glyconanomaterial in lectin binding and bacterial imaging. The cellulose nanocrystals were prepared by TEMPO-mediated oxidation and acidic hydrolysis, followed by functionalization with a quinolone fluorophore and carbohydrate ligands. The cellulose nanocrystals were subsequently applied in interaction studies with carbohydrate-binding proteins and in bacterial imaging. The results show that the functional cellulose nanocrystals could selectively recognize the corresponding cognate lectins. In addition, mannosylated nanocrystals were shown to selectively interact with FimH-presenting E. coli, as detected by TEM and confocal fluorescence microscopy. These glyconanomaterials provide a new application of cellulose nanocrystals in biorecognition and imaging.

Indexed as

CelluloseEscherichia coliLectinsMicroscopy, Electron, TransmissionNanofibersNanoparticlesProtein BindingCelluloseLectins

Identifiers

PMID25738860
PMCPMC4492546

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.