Evidence map›Paper›PMID 2573813›Full record

ArticleLipids1989

Feeding pure docosahexaenoate or arachidonate decreases plasma triacylglycerol secretion in rats.

M A Williams, J Tinoco, Y T Yang, M I Bird, I Hincenbergs

Abstract read
PubMed Publisher
In one paragraph

Article in Lipids, 1989. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
1.8field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 33 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

M A WilliamsDepartment of Nutritional Sciences, University of California, Berkeley 94720.
J Tinoco
Y T Yang
M I Bird
I Hincenbergs
University of California, Berkeley · USInternational Tin Research Institute · GBMerck & Co., Inc., Rahway, NJ, USA (United States) · US

Funding

NIADDK NIH HHS R01-AM12024
6 · The paper itself

Abstract

Essential fatty acid (EFA)-deficient rats were fed highly purified methyl esters of docosahexaenoate (22:6n-3), arachidonate (20:4n-6), alpha-linolenate (18:3n-3) or oleate (18:1n-9) (100 mg/day, tube fed for 3-10 days), and their plasma triacylglycerol (TG) secretion rates were measured. Secretion rates of TG into plasma were reduced by tube-feeding 22:6n-3, 20:4n-6, 18:3n-3, but not 18:1n-9, to EFA-deficient rats. A significant reduction occurred after feeding 22:6n-3 for only three days. Feeding 22:6n-3 or 18:3n-3 to EFA-deficient rats for three days also reduced the activities of liver lipogenic enzymes and sharply increased the proportions of 22:6n-3 and 20:5n-3 in liver phospholipid fractions. Mechanisms by which these EFA may reduce lipogenesis are discussed.

Indexed as

alpha-Linolenic AcidAnimalsArachidonic AcidArachidonic AcidsATP Citrate (pro-S)-LyaseDietary FatsDocosahexaenoic AcidsLinolenic AcidsLiverMalate DehydrogenaseMalePhospholipidsRatsRats, Inbred StrainsTriglyceridesalpha-Linolenic AcidArachidonic AcidArachidonic AcidsATP Citrate (pro-S)-LyaseDietary FatsDocosahexaenoic AcidsLinolenic AcidsMalate DehydrogenasePhospholipidsTriglycerides

Identifiers

PMID2573813
OpenAlexW2056545722

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.