Evidence map›Paper›PMID 25738121›Full record

ArticleNephro-urology monthly2015

Isolated anti-hbc and occult HBV infection in dialysis patients.

Amitis Ramezani, Mohammad Reza Aghasadeghi, Farrokhlagha Ahmadi, Effat Razeghi, Ali Eslamifar, Mohammad Banifazl, Masoomeh Sofian, Golnaz Bahramali, Soheila Hekmat, Arezoo Aghakhani

Open access · hybridAbstract read
In one paragraph

Article in Nephro-urology monthly, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 26 citations in OpenAlex.

  1. Article
  2. Article
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  4. Article
  5. Article
  6. Observational
  7. Article
  8. Update on occult hepatitis B virus infection.World journal of gastroenterology · 2016
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Amitis RamezaniDepartment of Clinical Research, Pasteur Institute of Iran, Tehran, IR Iran.
Mohammad Reza AghasadeghiDepartment of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, IR Iran.
Farrokhlagha AhmadiNephrology Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Effat RazeghiNephrology Research Center, Tehran University of Medical Sciences, Tehran, IR Iran.
Ali EslamifarDepartment of Clinical Research, Pasteur Institute of Iran, Tehran, IR Iran.
Mohammad BanifazlIranian Society for Support Patients With Infectious Diseases, Tehran, IR Iran.
Masoomeh SofianTPIRC (Tuberculosis and Pediatric Infectious Research Center), Arak University of Medical Sciences, Arak, IR Iran.
Golnaz BahramaliDepartment of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, IR Iran.
Soheila HekmatDepartment of Hepatitis and AIDS, Pasteur Institute of Iran, Tehran, IR Iran.
Arezoo AghakhaniDepartment of Clinical Research, Pasteur Institute of Iran, Tehran, IR Iran.
Pasteur Institute of Iran · IRTehran University of Medical Sciences · IRArak University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundOccult Hepatitis B virus (HBV) infection (OBI) is defined as the presence of HBV-DNA in the liver or serum with undetectable hepatitis B surface antigen (HBsAg). Hemodialysis (HD) patients are at risk of acquiring parenterally transmitted infections.

objectivesThe aim of this study was to assess the prevalence of OBI in HD patients. PATIENTS AND

methodsA hundred HBsAg negative HD patients were included in this study from main dialysis units in Tehran, Iran. HBsAg, hepatitis B surface antibody (anti-HBs), hepatitis B core antibody (anti-HBc) and liver enzymes levels were examined in all subjects. The presence of HBV-DNA was determined in plasma samples using real-time PCR.

resultsA hundredpatients with a mean age of 58.5 ± 16.1 years were enrolled in this study. In total, 56.7% were male and 43.3% female. Anti-HBs, anti-HBc, anti-HCV and anti-HIV were detected in 56.7%, 2%, 5.2% and 1% of patients, respectively. Isolated anti-HBc was detected in 2% of cases. HBV-DNA was detected in 1% of HBsAg negative patients.

conclusionsThis study showed a low rate of isolated anti-HBc and occult HBV infection in HD patients. It can be due to improvement of people's knowledge about HBV transmission routes, HBV vaccination of HD patients and regular surveillance of HBV infection.

Indexed as

HemodialysisHepatitis B virusInfection

Identifiers

PMID25738121
PMCPMC4330694
OpenAlexW2129523842

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.