ArticleSaudi journal of biological sciences2015
Influence of olive and rosemary leaves extracts on chemically induced liver cirrhosis in male rats.
Article in Saudi journal of biological sciences, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.
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Who cites it
17 citing papers in PubMed, 51 citations in OpenAlex.
- Nanoparticles from grape seed extract inhibit inflammatory cytokines and ameliorate CClBMC complementary medicine and therapies · 2025Article
- Antioxidant Synergy in a Mixture of Powder Plant Leaves and Effects on Metabolic Profile, Oxidative Status and Intestinal Morpho-Histochemical Features of Laying Hens.Animals : an open access journal from MDPI · 2025Article
- Promising Therapeutic Treatments for Cardiac Fibrosis: Herbal Plants and Their Extracts.Cardiology and therapy · 2023Review
- Effect of Empagliflozin on Thioacetamide-Induced Liver Injury in Rats: Role of AMPK/SIRT-1/HIF-1α Pathway in Halting Liver Fibrosis.Antioxidants (Basel, Switzerland) · 2022Article
- Antioxidant, anti-inflammatory, and anti-fibrotic properties of olive leaf extract protect against L-arginine induced chronic pancreatitis in the adult male albino rat.Anatomy & cell biology · 2022Article
- Hematological and biochemical investigations on the effect of curcumin and Thymoquinone in male mice exposed to Thioacetamide.Saudi journal of biological sciences · 2022Article
- Article
- The Impact of Herbal Infusion Consumption on Oxidative Stress and Cancer: The Good, the Bad, the Misunderstood.Molecules (Basel, Switzerland) · 2020Review
- Potential Hepatoprotective Activity of Super Critical Carbon Dioxide Olive Leaf Extracts against CClFoods (Basel, Switzerland) · 2020Article
- Influence of olive leaves extract on hepatorenal injury in streptozotocin diabetic rats.Saudi journal of biological sciences · 2019Article
- Cellular proliferation/cytotoxicity and antimicrobial potentials of green synthesized silver nanoparticles (AgNPs) usingSaudi journal of biological sciences · 2019Article
- The potential protective influence of flaxseed oil against renal toxicity induced by thioacetamide in rats.Saudi journal of biological sciences · 2018Article
- Antioxidant and Antimicrobial Properties of Rosemary (Medicines (Basel, Switzerland) · 2018Review
- Clinical value of liver and spleen shear wave velocity in predicting the prognosis of patients with portal hypertension.World journal of gastroenterology · 2017Observational
- Chemoprotective effect of omega-3 fatty acids on thioacetamide induced hepatic fibrosis in male rats.Saudi journal of biological sciences · 2017Article
- Ameliorative Effect of Vanillic Acid on Serum Bilirubin, Chronotropic and Dromotropic Properties in the Cholestasis-Induced Model Rats.Electronic physician · 2016Article
- Effect of Olea oleaster and Juniperus procera leaves extracts on thioacetamide induced hepatic cirrhosis in male albino mice.Saudi journal of biological sciences · 2016Article
Corrections and comments
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Authors and funding
2 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The current study was undertaken to evaluate the protective activity of olive and rosemary leaves extracts on experimental liver cirrhosis induced by thioacetamide (TAA) in Wistar male rats. Highly significant decline in the values of body weight gain and highly statistically increase of liver/body weight ratio were noted in rats treated with TAA. Furthermore, the levels of serum alanine aminotransferase, aspartate aminotransferase, gamma glutamyl transferase, alkaline phosphatase and total bilirubin were statistically increased. Additionally, light microscopic examination of liver sections from rats treated with TAA showed a marked increase in the extracellular matrix collagen content and bridging fibrosis was prominent. There were bundles of collagen surrounding the lobules that resulted in large fibrous septa and distorted tissue architecture. Interestingly, the findings of this experimental study indicated that the extracts of olive and rosemary leaves and their combination possess hepatoprotective properties against TAA-induced hepatic cirrhosis by inhibiting the physiological and histopathological alterations. Moreover, these results suggest that the hepatoprotective effects of these extracts may be attributed to their antioxidant activities.
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.