Evidence map›Paper›PMID 25737052›Full record

ReviewVeterinary parasitology2015

An update on Sarcocystis neurona infections in animals and equine protozoal myeloencephalitis (EPM).

J P Dubey, D K Howe, M Furr, W J Saville, A E Marsh, S M Reed, M E Grigg

Abstract readReview
In one paragraph

Review in Veterinary parasitology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 110 citations in OpenAlex.

  1. Article
  2. Article
  3. Persistence ofFrontiers in veterinary science · 2026
    Article
  4. Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  5. Article
  6. Molecular identification ofJournal of parasitic diseases : official organ of the Indian Society for Parasitology · 2024
    Article
  7. Identification ofVeterinary sciences · 2024
    Article
  8. Article
  9. Reactivity against Sarcocystis neurona and Sarcocystis falcatula-like in horses from Southeastern and Midwestern Brazil.Revista brasileira de parasitologia veterinaria = Brazilian journal of veterinary parasitology : Orgao Oficial do Colegio Brasileiro de Parasitologia Veterinaria · 2023
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Reactivity of Horse Sera to Antigens Derived FromFrontiers in veterinary science · 2020
    Article
  16. Article
  17. Article
  18. High-throughput screen of drug repurposing library identifies inhibitors of Sarcocystis neurona growth.International journal for parasitology. Drugs and drug resistance · 2018
    Article
  19. Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 6 institutions in 1 country.

J P DubeyUnited States Department of Agriculture, Agricultural Research Service, Animal Parasitic Diseases Laboratory, Beltsville Agricultural Research Center, Building 1001, Beltsville, MD 20705-2350, USA. Electronic address: Jitender.dubey@ars.usda.gov.
D K HoweM.H. Gluck Equine Research Center, Department of Veterinary Science, University of Kentucky, Lexington, KY 40546-0099, USA.
M FurrMarion du Pont Scott Equine Medical Center, Virginia Maryland Regional College of Veterinary Medicine, 17690 Old Waterford Road, Leesburg, VA 20176, USA.
W J SavilleDepartment of Veterinary Preventive Medicine, The Ohio State University, 1920 Coffey Road, Columbus, OH 43210, USA.
A E MarshDepartment of Veterinary Preventive Medicine, The Ohio State University, 1920 Coffey Road, Columbus, OH 43210, USA.
S M ReedRood and Riddle Equine Hospital, Lexington, KY 40511, USA.
M E GriggMolecular Parasitology Section, Laboratory of Parasitic Diseases, National Institutes of Health, National Institutes of Allergy, and Infectious Diseases, 4 Center Drive, Room B1-06, Bethesda, MD 20892, USA.
The Ohio State University · USMarion duPont Scott Equine Medical Center · USNational Institute of Allergy and Infectious Diseases · USRood and Riddle Equine Hospital · USUnited States Department of Agriculture · USUniversity of Kentucky · US

Funding

Toxoplasma Population GeneticsZIAAI001018 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI GRIGG, MICHAEL · 2009 to 2025
$11.3M
Toxoplasma Population GeneticsZ01AI001018 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI GRIGG, MICHAEL · 2007 to 2008
$801k
Intramural NIH HHS Z01 AI001018
6 · The paper itself

Abstract

Equine protozoal myeloencephalitis (EPM) is a serious disease of horses, and its management continues to be a challenge for veterinarians. The protozoan Sarcocystis neurona is most commonly associated with EPM. S. neurona has emerged as a common cause of mortality in marine mammals, especially sea otters (Enhydra lutris). EPM-like illness has also been recorded in several other mammals, including domestic dogs and cats. This paper updates S. neurona and EPM information from the last 15 years on the advances regarding life cycle, molecular biology, epidemiology, clinical signs, diagnosis, treatment and control.

Indexed as

AnimalsAntiprotozoal AgentsEncephalomyelitisProtozoan Infections, AnimalSarcocystisSarcocystosisAntiprotozoal AgentsEpidemiologyEquine protozoal myeloencephalitisLife cycleMarine mammalsPreventionSarcocystis neurona

Identifiers

PMID25737052
PMCPMC4461864
OpenAlexW2020115461

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.