ArticleInsights into imaging2015
Thyroid nodule ultrasound: technical advances and future horizons.
Article in Insights into imaging, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
20 citing papers in PubMed, 40 citations in OpenAlex.
- Trial
- Application of transformer attention mechanism-based multimodal deep learning model in the diagnosis of papillary thyroid carcinoma.BMC medical imaging · 2026Article
- Evaluation and Management of Thyroid Nodules: A Joint Consensus Statement From the British Thyroid Association (BTA), British Association of Endocrine and Thyroid Surgeons (BAETS) and Collaborating Bodies.Clinical endocrinology · 2026Article
- Study of French inter-expert variability in thyroid nodule ultrasound.European thyroid journal · 2026Article
- Roadmap for Representative Artificial Intelligence Models for Thyroid Cancer.The Laryngoscope · 2026Review
- ThyroidNet: A Deep Learning Network for Localization and Classification of Thyroid Nodules.Computer modeling in engineering & sciences : CMES · 2023Article
- Interaction of MRPL9 and GGCT Promotes Cell Proliferation and Migration by Activating the MAPK/ERK Pathway in Papillary Thyroid Cancer.International journal of molecular sciences · 2022Article
- Added value of mass characteristic frequency to 2-D shear wave elastography for differentiation of benign and malignant thyroid nodules.Ultrasound in medicine & biology · 2022Article
- Non-Toxic Multinodular Goiter: From Etiopathogenesis to Treatment.Sisli Etfal Hastanesi tip bulteni · 2022Review
- Molecular Testing for Thyroid Nodules Including Its Interpretation and Use in Clinical Practice.Annals of surgical oncology · 2021Review
- Bilateral thyroid adenomas in an alpaca.Journal of veterinary internal medicine · 2021Article
- Adiponectin and Thyroid Cancer: Insight into the Association between Adiponectin and Obesity.Aging and disease · 2021Review
- Characterization of immune landscape in papillary thyroid cancer reveals distinct tumor immunogenicity and implications for immunotherapy.Oncoimmunology · 2021Article
- Different sonographic features of peripheral thyroid nodule calcification and risk of malignancy: a prospective observational study.Polish journal of radiology · 2021Article
- Multimode ultrasonic technique is recommended for the differential diagnosis of thyroid cancer.PeerJ · 2020Article
- Diagnostic accuracy of ultrasound characteristics in the identification of malignant thyroid nodules.BMC research notes · 2019Article
- Nodular Thyroid Disease and Thyroid Cancer in the Era of Precision Medicine.European thyroid journal · 2017Review
- Thyroid computed tomography imaging: pictorial review of variable pathologies.Insights into imaging · 2016Review
- Quantitative analysis of suspicious thyroid nodules by contrast-enhanced ultrasonography.International journal of clinical and experimental medicine · 2015Article
- The sensitivity of TIRADS scoring on ultrasonography in the management of thyroid nodules.Pakistan journal of medical sciencesArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
unlabelledThyroid nodules are extremely common and the vast majority are non-malignant; therefore the accurate discrimination of a benign lesion from malignancy is challenging. Ultrasound (US) characterisation has become the key component of many thyroid nodule guidelines and is primarily based on the detection of key features by high-resolution US. The thyroid imager should be familiar with the strengths and limitations of this modality and understand the technical factors that create and alter the imaging characteristics. Specific advances in high-resolution US are discussed with reference to individual features of thyroid cancer and benign disease. Potential roles for three-dimensional thyroid ultrasound and computer-aided diagnosis are also considered. The second section provides an overview of current evidence regarding thyroid ultrasound elastography (USE). USE is a novel imaging technique that quantifies tissue elasticity (stiffness) non-invasively and has potential utility because cancers cause tissue stiffening. In recent years, there has been much research into the value of thyroid USE for distinguishing benign and malignant nodules. Preliminary findings from multiple pilot studies and meta-analyses are promising and suggest that USE can augment the anatomical detail provided by high-resolution US. However, a definite role remains controversial and is discussed. TEACHING POINTS: • High-resolution US characterises thyroid nodules by demonstration of specific anatomical features • Technical advances heavily influence the key US features of thyroid nodules • Most papillary carcinomas appear stiffer than benign thyroid nodules on US elastography (USE) • Thyroid USE is controversial because of variation in the reported accuracies for malignancy • Combined grey-scale US/USE may lower the FNAC rate in benign nodules.
Identifiers
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.