Evidence map›Paper›PMID 25736442›Full record

ArticleJournal of the American Heart Association2015

Moderate-to-vigorous physical activity with accelerometry is associated with visceral adipose tissue in adults.

Joanne M Murabito, Alison Pedley, Joseph M Massaro, Ramachandran S Vasan, Dale Esliger, Susan J Blease, Udo Hoffman, Caroline S Fox

Abstract readComparative Study
In one paragraph

Article in Journal of the American Heart Association, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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  16. 70-year legacy of the Framingham Heart Study.Nature reviews. Cardiology · 2019
    Review
  17. Article
  18. Physical Activity Following Positive Airway Pressure Treatment in Adults With and Without Obesity and With Moderate-Severe Obstructive Sleep Apnea.Journal of clinical sleep medicine : JCSM : official publication of the American Academy of Sleep Medicine · 2018
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Joanne M MurabitoDepartment of Medicine, Section of General Internal Medicine, Section of Preventive Medicine, Boston University School of Medicine, Boston, MA (J.M.M., R.S.V.) National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.).
Alison PedleyNational Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.).
Joseph M MassaroNational Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.) Department of Biostatistics, Boston University School of Public Health, Boston, MA (J.M.M.).
Ramachandran S VasanDepartment of Medicine, Section of General Internal Medicine, Section of Preventive Medicine, Boston University School of Medicine, Boston, MA (J.M.M., R.S.V.) National Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.).
Dale EsligerSchool of Sport, Exercise and Health Sciences, Loughborough University, UK (D.E.).
Susan J BleaseNational Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.).
Udo HoffmanDepartment of Cardiac MR PET CT & Harvard Medical School, Massachusetts General Hospital, Boston, MA (U.H.).
Caroline S FoxNational Heart, Lung and Blood Institute's Framingham Heart Study, Framingham, MA (J.M.M., A.P., J.M.M., R.S.V., S.J.B., C.S.F.) Division of Intra-mural Research and the Center for Population Studies, National Heart, Lung and Blood Institute, Framingham, MA (C.S.F.) Division of Endocrinology & Harvard Medical School, Brigham and Women's Hospital, Boston, MA (C.S.F.).

Funding

Framingham Heart Study/FoxZIAHL006094 · NHLBI · NATIONAL HEART, LUNG, AND BLOOD INSTITUTE · PI FOX, CAROLINE · 2010 to 2015
$6.9M
Physical Activity, Cardiometabolic Risk, and Target-Organ Damage in Older AdultsR01AG047645 · NIA · BOSTON UNIVERSITY MEDICAL CAMPUS · PI RAMACHANDRAN, VASAN S · 2014 to 2015
$661k
THE FRAMINGHAM HEART STUDY-N01HC25195-268025195-268025195N01HC025195 · HC · TRUSTEES OF BOSTON UNIVERSITY · PI WOLF, PHILIP A · 2002 to 2006
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NHLBI NIH HHS N01-HC-25195NIA NIH HHS R01 AG047645NIA NIH HHS R01AG047645
6 · The paper itself

Abstract

backgroundWe examined the relation between objectively measured physical activity with accelerometry and subcutaneous adipose tissue (SAT) and visceral adipose tissue (VAT) in a community-based sample. METHODS AND

resultsWe evaluated 1249 participants of the Framingham Third Generation and Omni II cohorts (mean age 51.7 years, 47% women) who underwent assessment of moderate-to-vigorous physical activity (MVPA) with accelerometry over 5 to 7 days, and multi-detector computed tomography for measurement of SAT and VAT volume; fat attenuation was estimated by SAT and VAT hounsfield units (HU). In women, higher levels of MVPA were associated with decreased SAT (P<0.0001) and VAT volume (P<0.0001). The average decrement in VAT per 30 minute/day increase in MVPA was -453 cm(3) (95% CI -574, -331). The association was attenuated but persisted upon adjustment for BMI (-122 cm(3), P=0.002). Higher levels of MVPA were associated with higher SAT HU (all P≤0.01), a marker of fat quality, even after adjustment for SAT volume. Similar findings were observed in men but the magnitude of the association was less. Sedentary time was not associated with SAT or VAT volume or quality in men or women.

conclusionsMVPA was associated with less VAT and SAT and better fat quality.

Indexed as

ActigraphyAdiposityMotor ActivityMultidetector Computed TomographyAdultFemaleHumansIntra-Abdominal FatMaleMiddle AgedObesityOrgan SizePredictive Value of TestsRisk FactorsSedentary BehaviorSex Factorsaccelerometryphysical activityvisceral adipose tissue

Identifiers

PMID25736442
PMCPMC4392428

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.