Evidence map›Paper›PMID 25735843›Full record

ArticleThe Journal of antibiotics2015

Adipostatins A-D from Streptomyces sp. 4875 inhibiting Brugia malayi asparaginyl-tRNA synthetase and killing adult Brugia malayi parasites.

Mostafa E Rateb, Dong Yang, Sanja Vodanovic-Jankovic, Zhiguo Yu, Michael A Kron, Ben Shen

Open access · bronzeAbstract read
PubMed Publisher
In one paragraph

Article in The Journal of antibiotics, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.8field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 14 citations in OpenAlex.

  1. Article
  2. Review
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mostafa E RatebDepartment of Chemistry, The Scripps Research Institute, Jupiter, FL, USA.
Dong YangDepartment of Chemistry, The Scripps Research Institute, Jupiter, FL, USA.
Sanja Vodanovic-JankovicBiotechnology and Bioengineering Center and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Zhiguo YuDepartment of Chemistry, The Scripps Research Institute, Jupiter, FL, USA.
Michael A KronBiotechnology and Bioengineering Center and Department of Medicine, Medical College of Wisconsin, Milwaukee, WI, USA.
Ben ShenDepartment of Chemistry, The Scripps Research Institute, Jupiter, FL, USA.
Scripps Research Institute · USMedical College of Wisconsin · US

Funding

Macrofilaricidal Aminoacyl-tRNA Synthetase InhibitorsU01AI053877 · NIAID · MICHIGAN STATE UNIVERSITY · PI KRON, MICHAEL A. · 2002 to 2006
$2.9M
Natural products as antifilarial asparaginyl-tRNA synthetase inhibitorsR21AI105472 · NIAID · MEDICAL COLLEGE OF WISCONSIN · PI KRON, MICHAEL A., SHEN, BEN · 2013 to 2014
$475k
NIAID NIH HHS AI053877NIAID NIH HHS AI105472
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AnimalsAspartate-tRNA LigaseBrugia malayiFilaricidesMagnetic Resonance SpectroscopyMolecular StructureResorcinolsRNA, Transfer, Amino AcylStreptomycesSurvival Analysisasparaginyl-tRNA synthetaseAspartate-tRNA LigaseFilaricidesResorcinolsRNA, Transfer, Amino Acyl

Identifiers

PMID25735843
OpenAlexW2049163923

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.