ArticleScientific reports2015
Microscale magnetic field modulation for enhanced capture and distribution of rare circulating tumor cells.
Article in Scientific reports, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.
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The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
27 citing papers in PubMed.
- Numerical Studies on the Motions of Magnetically Tagged Cells Driven by a Micromagnetic Matrix.Micromachines · 2023Article
- Magnetic force-based cell manipulation forAPL bioengineering · 2023Review
- Measuring antigen expression of cancer cell lines and circulating tumour cells.Scientific reports · 2023Article
- Directed Assembly of Nanomaterials for Making Nanoscale Devices and Structures: Mechanisms and Applications.ACS nano · 2022Review
- Droplet Manipulation under a Magnetic Field: A Review.Biosensors · 2022Review
- Microfluidic-Based Technologies for CTC Isolation: A Review of 10 Years of Intense Efforts towards Liquid Biopsy.International journal of molecular sciences · 2022Review
- Manipulation of single cells via a Stereo Acoustic Streaming Tunnel (SteAST).Microsystems & nanoengineering · 2022Article
- Optimal Halbach Configuration for Flow-through Immunomagnetic CTC Enrichment.Diagnostics (Basel, Switzerland) · 2021Article
- Magnetic Particles for CTC Enrichment.Cancers · 2020Review
- Magnetically driven microfluidics for isolation of circulating tumor cells.Cancer medicine · 2020Review
- Simulation of circulating tumor cell transport and adhesion in cell suspensions in microfluidic devices.Biomicrofluidics · 2019Article
- Development of a microfluidic platform for size-based hydrodynamic enrichment and PSMA-targeted immunomagnetic isolation of circulating tumour cells in prostate cancer.Biomicrofluidics · 2019Article
- Capturing magnetic bead-based arrays using perpendicular magnetic anisotropy.Applied physics letters · 2019Article
- Microfluidics-enabled rapid manufacturing of hierarchical silica-magnetic microflower toward enhanced circulating tumor cell screening.Biomaterials science · 2018Article
- Microfluidics-enabled rational design of immunomagnetic nanomaterials and their shape effect on liquid biopsy.Lab on a chip · 2018Article
- Advances in liquid biopsy on-chip for cancer management: Technologies, biomarkers, and clinical analysis.Critical reviews in clinical laboratory sciences · 2018Review
- Numerical simulation of cell squeezing through a micropore by the immersed boundary method.Proceedings of the Institution of Mechanical Engineers. Part C. Journal of mechanical engineering science · 2018Article
- Magnetic Force-Based Microfluidic Techniques for Cellular and Tissue Bioengineering.Frontiers in bioengineering and biotechnology · 2018Review
- Materials and microfluidics: enabling the efficient isolation and analysis of circulating tumour cells.Chemical Society reviews · 2017Review
- Improving sensitivity and specificity of capturing and detecting targeted cancer cells with anti-biofouling polymer coated magnetic iron oxide nanoparticles.Colloids and surfaces. B, Biointerfaces · 2017Article
Corrections and comments
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Authors and funding
4 authors.
Funding
Abstract
Immunomagnetic assay combines the powers of the magnetic separation and biomarker recognition and has been an effective tool to perform rare Circulating Tumor Cells detection. Key factors associated with immunomagnetic assay include the capture rate, which indicates the sensitivity of the system, and distributions of target cells after capture, which impact the cell integrity and other biological properties that are critical to downstream analyses. Here we present a theoretical framework and technical approach to implement a microscale magnetic immunoassay through modulating local magnetic field towards enhanced capture and distribution of rare cancer cells. Through the design of a two-dimensional micromagnet array, we characterize the magnetic field generation and quantify the impact of the micromagnets on rare cell separation. Good agreement is achieved between the theory and experiments using a human colon cancer cell line (COLO205) as the capture targets.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.