Evidence map›Paper›PMID 25735468›Full record

ArticleDrug and alcohol dependence2015

Factors associated with being asked to initiate someone into injection drug use.

Ricky N Bluthenthal, Lynn Wenger, Daniel Chu, Jennifer Lorvick, Brendan Quinn, James P Thing, Alex H Kral

Abstract read
In one paragraph

Article in Drug and alcohol dependence, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ricky N BluthenthalDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States. Electronic address: rbluthen@usc.edu.
Lynn WengerUrban Health Program, RTI International, 351 California Street, San Francisco, CA 94104, United States.
Daniel ChuDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States.
Jennifer LorvickUrban Health Program, RTI International, 351 California Street, San Francisco, CA 94104, United States.
Brendan QuinnCentre for Population Health, Burnet Institute, 85 Commercial Road, Melbourne, VIC 3004, Australia.
James P ThingDepartment of Preventive Medicine, Institute for Prevention Research, Keck School of Medicine, University of Southern California, Los Angeles, CA 90033, United States; Department of Family and Consumer Sciences, McClelland Institute for Children Youth and Families, University of Arizona, Tucson, AZ 85721, United States.
Alex H KralUrban Health Program, RTI International, 351 California Street, San Francisco, CA 94104, United States.

Funding

USC/NORRIS COMPREHENSIVE CANCER CENTER (CORE) SUPPORTP30CA014089 · NCI · UNIVERSITY OF SOUTHERN CALIFORNIA · PI MYLES G COCKBURN · 1985 to 2026
$181.4M
Exploratory Research on Late Initiation of Drug InjectionR01DA027689 · NIDA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI BLUTHENTHAL, RICKY N, KRAL, ALEXANDER H · 2010 to 2012
$1.7M
NCI NIH HHS P30 CA014089NCI NIH HHS P30CA014089NIDA NIH HHS R01 DA027689NIDA NIH HHS R01DA027689
6 · The paper itself

Abstract

aimsInjection drug use initiation typically involves an established person who injects drugs (PWID) helping the injection-naïve person to inject. Prior to initiation, PWID may be involved in behaviors that elevate injection initiation risk for non-injectors such as describing how to inject and injecting in front of injection-naïve people. In this analysis, we examine whether PWID who engage in either of these behaviors are more likely to be asked to initiate someone into drug injection.

methodsInterviews with PWID (N = 602) were conducted in California between 2011 and 2013. Multivariate analysis was conducted to determine factors associated with being asked to initiate someone.

resultsThe sample was diverse in terms of age, race/ethnicity, and drug use patterns. Seventy-one percent of the sample had ever been asked to initiate someone. Being asked to initiate someone was associated with having injected in front of non-injectors (Adjusted Odds Ratio [AOR] = 1.80, 95% Confidence Interval [CI] = 1.12, 2.91), having described injection to non-injectors (AOR = 3.63; 95% CI = 2.07, 6.36), and doing both (AOR = 9.56; 95% CI = 4.43, 20.65) as compared to doing neither behavior (referent). Being female (AOR = 1.73; 95% CI = 1.10, 2.73) and non-injection prescription drug misuse in the last 30 days (AOR = 1.69; 95% CI = 1.12, 2.53) were also associated with having been asked to initiate someone.

conclusionReducing initiation into injection drug use is an important public health goal. Intervention development to prevent injection initiation should include established PWID and focus on reducing behaviors associated with requests to initiate injection and reinforcing refusal skills and intentions among established PWID.

Indexed as

AdolescentDrug UsersEthnicityFemaleHumansMaleMultivariate AnalysisSubstance Abuse, IntravenousYoung AdultInjection initiationObservational epidemiologyPWIDRequest to initiateSocial learning theory

Identifiers

PMID25735468
PMCPMC5048683

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.