Evidence map›Paper›PMID 25735305›Full record

ArticleThe Journal of general virology2015

Genetic analysis of members of the species Oropouche virus and identification of a novel M segment sequence.

Natasha L Tilston-Lunel, Joseph Hughes, Gustavo Olszanski Acrani, Daisy E A da Silva, Raimunda S S Azevedo, Sueli G Rodrigues, Pedro F C Vasconcelos, Marcio R T Nunes, Richard M Elliott

Open access · hybridAbstract read
In one paragraph

Article in The Journal of general virology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed, 2 pooled it
3.1field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed, 2 syntheses or guidelines pooled it, 96 citations in OpenAlex.

  1. Pooled it
  2. A bibliometric analysis of Oropouche virus.Frontiers in microbiology · 2024
    Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Natasha L Tilston-Lunel1MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow G61 1QH, Scotland, UK 2Biomedical Sciences Research Complex, School of Biology, University of St Andrews, St Andrews KY16 9ST, Scotland, UK.
Joseph Hughes1MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow G61 1QH, Scotland, UK.
Gustavo Olszanski Acrani1MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow G61 1QH, Scotland, UK 3Department of Cell and Molecular Biology, University of Sao Paulo School of Medicine, 3900, Av Bandeirantes, Ribeirão Preto, SP 14049-900, Brazil.
Daisy E A da Silva4Center for Technological Innovation, Instituto Evandro Chagas, Ananindeua, Brazil.
Raimunda S S Azevedo5Department of Arbovirology and Hemorrhagic Fevers, Instituto Evandro Chagas, Ananindeua, Brazil.
Sueli G Rodrigues5Department of Arbovirology and Hemorrhagic Fevers, Instituto Evandro Chagas, Ananindeua, Brazil.
Pedro F C Vasconcelos5Department of Arbovirology and Hemorrhagic Fevers, Instituto Evandro Chagas, Ananindeua, Brazil.
Marcio R T Nunes4Center for Technological Innovation, Instituto Evandro Chagas, Ananindeua, Brazil.
Richard M Elliott1MRC-University of Glasgow Centre for Virus Research, 464 Bearsden Road, Glasgow G61 1QH, Scotland, UK.
Instituto Evandro Chagas · BRMRC University of Glasgow Centre for Virus Research · GBUniversidade de São Paulo · BRUniversity of St Andrews · GB

Funding

Medical Research Council 1101085Medical Research Council G0801822Wellcome TrustWellcome Trust 99220
6 · The paper itself

Abstract

Oropouche virus (OROV) is a public health threat in South America, and in particular in northern Brazil, causing frequent outbreaks of febrile illness. Using a combination of deep sequencing and Sanger sequencing approaches, we determined the complete genome sequences of eight clinical isolates that were obtained from patient sera during an Oropouche fever outbreak in Amapa state, northern Brazil, in 2009. We also report the complete genome sequences of two OROV reassortants isolatd from two marmosets in Minas Gerais state, south-east Brazil, in 2012 that contained a novel M genome segment. Interestingly, all 10 isolates possessed a 947 nt S segment that lacked 11 residues in the S-segment 3' UTR compared with the recently redetermined Brazilian prototype OROV strain BeAn19991. OROV maybe circulating more widely in Brazil and in the non-human primate population than previously appreciated, and the identification of yet another reassortant highlights the importance of bunyavirus surveillance in South America.

Indexed as

Genome, ViralAdolescentAdultAnimalsBrazilBunyaviridae InfectionsCallithrixCluster AnalysisFemaleHumansMaleMiddle AgedMolecular Sequence DataOrthobunyavirusPhylogenyReassortant VirusesRNA, Viral

Identifiers

PMID25735305
PMCPMC4635451
OpenAlexW2473135815

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.