Evidence map›Paper›PMID 25735200›Full record

Trial reportDrug and alcohol review2015

Pathways to change: Use trajectories following trauma-informed treatment of women with co-occurring post-traumatic stress disorder and substance use disorders.

Teresa López-Castro, Mei-Chen Hu, Santiago Papini, Lesia M Ruglass, Denise A Hien

Open access · greenAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Drug and alcohol review, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
25citing papers in PubMed, 2 pooled it
5.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

25 citing papers in PubMed, 2 syntheses or guidelines pooled it, 46 citations in OpenAlex.

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  9. A Social History of Opioids' Crimedical Cycle.Addiction research & theory · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 1 country.

Teresa López-CastroDepartment of Psychology, The City College of New York-CUNY, New York City, USA.
Mei-Chen Hu
Santiago Papini
Lesia M Ruglass
Denise A Hien
City College of New York · USColumbia University · USColumbia University Irving Medical Center · US

Funding

CU PARTNERS: NY/LONG ISLAND REGIONAL NODEU10DA013035 · NIDA · NEW YORK STATE PSYCHIATRIC INSTITUTE DBA RESEARCH FOUNDATION FOR MENTAL HYGIENE, INC · PI NUNES, EDWARD V., ROTROSEN, JOHN P · 2001 to 2015
$47.6M
A Randomized Trial of Concurrent Treatment for PTSD and Substance DependenceR01DA023187 · NIDA · CITY COLLEGE OF NEW YORK · PI HIEN, DENISE AIMEE · 2008 to 2011
$2.4M
NIDA NIH HHS R01 DA023187NIDA NIH HHS U10 DA013035NIDA NIH HHS U10 DA13035
6 · The paper itself

Abstract

INTRODUCTION AND

aimsDespite advances towards integration of care for women with co-occurring substance use disorder (SUD) and post-traumatic stress disorder (PTSD), low abstinence rates following SUD/PTSD treatment remain the norm. The utility of investigating distinct substance use trajectories is a critical innovation in the detection and refining of effective interventions for this clinical population. DESIGN AND

methodsThe present study reanalysed data from the largest randomised clinical trial to date for co-occurring SUD and PTSD in women (National Drug Abuse Treatment Clinical Trials Network; Women and Trauma Study). Randomised participants (n = 353) received one of two interventions in addition to treatment as usual for SUD: (i) trauma-informed integrative treatment for PTSD/SUD; or (ii) an active control psychoeducation course on women's health. The present study utilised latent growth mixture models (LGMM) with multiple groups to estimate women's substance use patterns during the 12-month follow-up period.

resultsFindings provided support for three different trajectories of substance use in the post-treatment year: (i) consistently low likelihood and use frequency; (ii) consistently high likelihood and use frequency; and (iii) high likelihood and moderate use frequency. Covariate analyses revealed improvement in PTSD severity was associated with membership in a specific substance use trajectory, although receiving trauma-informed treatment was not. Additionally, SUD severity, age and after-care efforts were shown to be related to trajectory membership. DISCUSSION AND

conclusionsFindings highlight the necessity of accounting for heterogeneity in post-treatment substance use, relevance of trauma-informed care in SUD recovery and benefits of incorporating methodologies like LGMM when evaluating SUD treatment outcomes.

Indexed as

Health EducationWomen's HealthAdultFemaleHumansLife Change EventsMiddle AgedStress Disorders, Post-TraumaticSubstance-Related DisordersTreatment Outcomelatent growth mixture modellingpost-traumatic stress disorderrelapsesubstance abusesubstance use trajectory

Identifiers

PMID25735200
PMCPMC7678790
OpenAlexW2140700904

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.