ReviewCurrent opinion in anaesthesiology2015
Perioperatively acquired disorders of coagulation.
Review in Current opinion in anaesthesiology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
15 citing papers in PubMed, 36 citations in OpenAlex.
- Development of the Novel G-CMAP Score: A Preoperative Scoring System for Predicting Postoperative Complications After Gastrectomy for Gastric Cancer.Annals of surgical oncology · 2026Article
- FXII decline during cardiopulmonary bypass and the limits of routine coagulation assays: a prospective observational analysis.Perioperative medicine (London, England) · 2026Article
- Comparative Analysis of Adhesive Strength and Flexibility in Surgical Sealants for Cardiovascular Surgery.Annals of vascular diseases · 2026Article
- Advancing Platelet Research Through Live-Cell Imaging: Challenges, Techniques, and Insights.Sensors (Basel, Switzerland) · 2025Review
- Association between delta anion gap/delta bicarbonate and outcome of surgical patients admitted to intensive care unit.BMC anesthesiology · 2024Observational
- Management of Coagulopathy in Bleeding Patients.Journal of clinical medicine · 2021Review
- Dynamic functional clot formation in patients undergoing endoscopic mucosal resection.JGH open : an open access journal of gastroenterology and hepatology · 2020Article
- Potential utility of new surgical hemostatic film using HydrofitJournal of artificial organs : the official journal of the Japanese Society for Artificial Organs · 2020Article
- Higher intraoperative plasma transfusion volumes are associated with inferior perioperative outcomes.Transfusion · 2019Article
- Incidence, features, in-hospital outcomes and predictors of in-hospital mortality associated with toxic megacolon hospitalizations in the United States.Internal and emergency medicine · 2018Article
- Interaction between warfarin and short-term intravenous amiodarone in intensive care unit patients after cardiac surgery.Journal of pharmaceutical health care and sciences · 2018Article
- Use of a flowable haemostat versus an oxidised regenerated cellulose agent in primary elective cardiac surgery: economic impact from a UK healthcare perspective.Journal of cardiothoracic surgery · 2017Article
- Efficacy of prothrombin complex concentrates for the emergency reversal of dabigatran-induced anticoagulation.Critical care (London, England) · 2016Review
- Massive hemorrhage management-a best evidence topic report.Therapeutics and clinical risk management · 2015Review
- Comparison of complications in open tracheostomy in patients taking low-dose aspirin.Science progressArticle
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 4 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purpose of reviewTo provide an overview of acquired coagulopathies that can occur in various perioperative clinical settings. Also described are coagulation disturbances linked to antithrombotic medications and currently available strategies to reverse their antithrombotic effects in situations of severe hemorrhage. RECENT
findingsRecent studies highlight the link between low fibrinogen and decreased fibrin polymerization in the development of acquired coagulopathy. Particularly, fibrin(ogen) deficits are observable after cardiopulmonary bypass in cardiac surgery, on arrival at the emergency room in trauma patients, and with ongoing bleeding after child birth. Regarding antithrombotic therapy, although new oral anticoagulants offer the possibility of efficacy and relative safety compared with vitamin K antagonists, reversal of their anticoagulant effect with nonspecific agents, including prothrombin complex concentrate, has provided conflicting results. Specific antidotes, currently being developed, are not yet licensed for clinical use, but initial results are promising. SUMMARY: Targeted hemostatic therapy aims to correct coagulopathies in specific clinical settings, and reduce the need for allogeneic transfusions, thus preventing massive transfusion and its deleterious outcomes. Although there are specific guidelines for reversing anticoagulation in patients treated with antiplatelet agents or warfarin, there is currently little evidence to advocate comprehensive recommendations to treat drug-induced coagulopathy associated with new oral anticoagulants.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.