Evidence map›Paper›PMID 25734812›Full record

ArticleThe Journal of investigative dermatology2015

Loss-of-Function Mutations in the Gene Encoding Filaggrin Are Not Strongly Associated with Chronic Actinic Dermatitis.

Catriona P Harkins, Alex Waters, Alastair Kerr, Linda Campbell, W H Irwin McLean, Sara J Brown, Sally H Ibbotson

Abstract readLetter
PubMed Full text at PMC Publisher
In one paragraph

Article in The Journal of investigative dermatology, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. The Immunogenetics of Photodermatoses.Advances in experimental medicine and biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catriona P HarkinsPhotobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.
Alex WatersPhotobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.
Alastair KerrPhotobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK.
Linda CampbellDermatology and Genetic Medicine, Division of Molecular Medicine, College of Life Sciences and College of Medicine, Dentistry and Nursing, University of Dundee, Dundee, Scotland, UK.
W H Irwin McLeanDermatology and Genetic Medicine, Division of Molecular Medicine, College of Life Sciences and College of Medicine, Dentistry and Nursing, University of Dundee, Dundee, Scotland, UK.
Sara J BrownDermatology and Genetic Medicine, Division of Cancer Research, College of Medicine, Dentistry and Nursing, Ninewells Hospital and Medical School, Dundee, Scotland, UK.
Sally H IbbotsonPhotobiology Unit, Department of Dermatology, University of Dundee, Ninewells Hospital and Medical School, Dundee, Scotland, UK. Electronic address: s.h.ibbotson@dundee.ac.uk.

Funding

Medical Research Council G0700314Medical Research Council G0802780Wellcome Trust 086398Wellcome Trust 086398/Z/08/ZWellcome Trust 098439Wellcome Trust 098439/Z/12/Z
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Genetic Predisposition to DiseaseMutationAdultAgedCase-Control StudiesFemaleFilaggrin ProteinsGene Expression RegulationHumansIntermediate Filament ProteinsMaleMiddle AgedPhotosensitivity DisordersSensitivity and SpecificityWhite PeopleYoung AdultFilaggrin ProteinsFLG protein, humanIntermediate Filament Proteins

Identifiers

PMID25734812
PMCPMC7116004

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.