Evidence map›Paper›PMID 25734738›Full record

ArticleJAMA2015

Pharmacological interventions for sleepiness and sleep disturbances caused by shift work.

Juha Liira, Jos Verbeek, Jani Ruotsalainen

Abstract readComment
PubMed Publisher
In one paragraph

Article in JAMA, 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
6.8field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 40 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Wellness: Combating Burnout and Its Consequences in Emergency Medicine.The western journal of emergency medicine · 2020
    Review
  8. Melatonin: A Molecule for Reducing Breast Cancer Risk.Molecules (Basel, Switzerland) · 2018
    Review
  9. Article
  10. Review
  11. ATS Core Curriculum 2016: Part I. Adult Sleep Medicine.Annals of the American Thoracic Society · 2016
    Article
  12. Synchrony and desynchrony in circadian clocks: impacts on learning and memory.Learning & memory (Cold Spring Harbor, N.Y.) · 2015
    Review
  13. The occupational health of Santa Claus.Journal of occupational medicine and toxicology (London, England) · 2015
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Juha LiiraFinnish Institute of Occupational Health, Helsinki, Finland.
Jos VerbeekFinnish Institute of Occupational Health, Helsinki, Finland.
Jani RuotsalainenFinnish Institute of Occupational Health, Helsinki, Finland.
Finnish Institute of Occupational Health · FI

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

clinical questionAre pharmacological interventions associated with better-quality sleep and alertness in shift workers? BOTTOM LINE: Low-quality evidence shows that melatonin is associated with 24 minutes longer daytime sleep after the shift but not with faster falling asleep compared with placebo. There is no association between hypnotics, such as zopiclone, and sleep outcomes, alertness, or harms. The alertness-promoting medications armodafinil and modafinil are associated with improved alertness during shift work but are also associated with headache and nausea.

Indexed as

HumansHypnotics and SedativesMelatoninSleepSleep Disorders, Circadian RhythmWakefulness-Promoting AgentsHypnotics and SedativesMelatoninWakefulness-Promoting Agents

Identifiers

PMID25734738
OpenAlexW3022198909

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.