Evidence map›Paper›PMID 25734419›Full record

ArticleMolecules (Basel, Switzerland)2015

Anti-tumor activity of a polysaccharide from blueberry.

Xiyun Sun, Ning Liu, Zhaoxia Wu, Ying Feng, Xianjun Meng

Open access · goldAbstract read
In one paragraph

Article in Molecules (Basel, Switzerland), 2015. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
7.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 35 citations in OpenAlex.

  1. Article
  2. Immunoregulatory Effects ofFoods (Basel, Switzerland) · 2024
    Article
  3. Extraction and Identification of Polysaccharide fromInternational journal of molecular sciences · 2024
    Article
  4. Article
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Xiyun SunCollege of Food, Shenyang Agricultural University, 120 Dongling Rd, Shenyang 110866, China. sun_xiyun@163.com.
Ning LiuCollege of Land and Environment, Shenyang Agricultural University, Shenyang 110866, China. lnbrisk@163.com.
Zhaoxia WuCollege of Food, Shenyang Agricultural University, 120 Dongling Rd, Shenyang 110866, China. wuzxsau@163.com.
Ying FengCollege of Food, Shenyang Agricultural University, 120 Dongling Rd, Shenyang 110866, China. fywjg@sina.com.
Xianjun MengCollege of Food, Shenyang Agricultural University, 120 Dongling Rd, Shenyang 110866, China. mengxjsy@126.com.
Shenyang Agricultural University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Blueberries (Vaccinium spp.) are rich in bioactive compounds. However, the biological activity of polysaccharides from blueberry has not been reported so far. This study evaluated the anti-tumor and immunological activities of a polysaccharide (BBP3-1) from blueberry in S180-bearing mice. The experimental results indicated that BBP3-1 (100 mg·kg-1·d-1) inhibited the tumor growth rate by 73.4%. Moreover, this group, compared with the model control, had shown an effect of increasing both the spleen and thymus indices (p < 0.05), increasing phagocytosis by macrophages (p < 0.05), boosting the proliferation and transformation of lymphocytes (p < 0.01), promoting the secretion of TNF-α, IFN-γ, and IL-2 (p < 0.05) and improving NK cell activity (p < 0.01). From this study, we could easily conclude that BBP3-1 has the ability to inhibit tumor progression and could act as a good immunomodulator.

Indexed as

AnimalsAntineoplastic AgentsBiological FactorsBlueberry PlantsCell Line, TumorCell ProliferationFemaleImmunologic FactorsInterferon-gammaInterleukin-2Killer Cells, NaturalMacrophagesMicePhagocytosisPlant ExtractsPolysaccharidesAntineoplastic AgentsBiological FactorsImmunologic FactorsInterferon-gammaInterleukin-2Plant ExtractsPolysaccharidesTumor Necrosis Factor-alpha

Identifiers

PMID25734419
PMCPMC6272434
OpenAlexW2038178350

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.